PARP2 Products

Description

PARP2 encodes poly(ADP-ribosyl)transferase-like 2 protein, which contains a catalytic domain and is capable of catalyzing a poly(ADP-ribosyl)ation reaction. This protein has a catalytic domain which is homologous to that of poly (ADP-ribosyl) transferase, but lacks an N-terminal DNA binding domain which activates the C-terminal catalytic domain of poly (ADP-ribosyl) transferase. The basic residues within the N-terminal region of this protein may bear potential DNA-binding properties, and may be involved in the nuclear and/or nucleolar targeting of the protein. Two alternatively spliced transcript variants encoding distinct isoforms have been found.

Bioinformatics

Uniprot	Q9UGN5 Human
Product By Gene ID	10038
Alternate Names	ADP-ribosyltransferase (NAD+; poly(ADP-ribose) polymerase)-like 2 ADPRT-2 ADPRT2pADPRT-2 ADPRTL2EC 2.4.2.30 ADPRTL3 hPARP-2 NAD(+) ADP-ribosyltransferase 2 PARP-2 poly (ADP-ribose) polymerase 2 poly (ADP-ribose) polymerase family, member 2 poly (ADP-ribosyl) transferase-like 2 poly [ADP-ribose] polymerase 2 poly(ADP-ribose) synthetase Poly[ADP-ribose] synthase 2 poly[ADP-ribose] synthetase 2

Research Areas for PARP2

Find related products by research area and learn more about each of the different research areas below.

DNA Repair
Hypoxia

Related PARP2 Blog Posts

Check out the latest blog posts on PARP2.

PARP Antibody Assays aid both Apoptosis and Cancer Research The PARP (Poly(ADP-ribose) polymerase) protein is a zinc-dependant nuclear enzyme whose main role is to detect and repair DNA single-strand breaks (SSB). However, PARP antibody research has revealed there are at least 17 PARP proteins, which also play...    Read more.

Read more PARP2 related blogs.