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Oncostatin M/OSM Products

Antibodies
Oncostatin M/OSM Antibody [Un ...
Oncostatin M/OSM Antibody [Unconju...
AF-495-NA
Species: Mu
Applications: WB, IHC, B/N
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
Formulation Catalog # Availability Price  
Oncostatin M/OSM Antibody (17 ...
Oncostatin M/OSM Antibody (17001)
MAB295
Species: Hu
Applications: WB, B/N, ELISA(Cap)
Host: Mouse Monoclonal
Formulation Catalog # Availability Price  
Oncostatin M/OSM Antibody (82 ...
Oncostatin M/OSM Antibody (824157)...
MAB4951
Species: Mu
Applications: B/N
Host: Rat Monoclonal
Formulation Catalog # Availability Price  
ELISA Kits
Human Oncostatin M (OSM) DuoS ...
Human Oncostatin M (OSM) DuoSet EL...
DY295
Species: Hu
Applications: ELISA
Mouse Oncostatin M (OSM) DuoS ...
Mouse Oncostatin M (OSM) DuoSet EL...
DY495-05
Species: Mu
Applications: ELISA
Mouse Oncostatin M (OSM) Quan ...
Mouse Oncostatin M (OSM) Quantikin...
MSM00
Species: Mu
Applications: ELISA
Lysates
Oncostatin M/OSM Overexpressi ...
Oncostatin M/OSM Overexpression Ly...
NBL1-14002
Species: Hu
Applications: WB
Proteins
Recombinant Human Oncostatin ...
Recombinant Human Oncostatin M (HE...
8475-OM
Species: Hu
Applications: Bioactivity
Formulation Catalog # Availability Price  
Recombinant Human Oncostatin ...
Recombinant Human Oncostatin M (OS...
295-OM
Species: Hu
Applications: Bioactivity
Formulation Catalog # Availability Price  
Recombinant Mouse Oncostatin ...
Recombinant Mouse Oncostatin M (OS...
495-MO
Species: Mu
Applications: Bioactivity
Formulation Catalog # Availability Price  

Description

Oncostatin M is a 252 amino acid protein that is 28 kDa, acts as growth regulator inhibiting the proliferation of a number of tumor cell lines and stimulating the proliferation of AIDS-KS cells; regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells; uses both type I OSM receptor (heterodimers composed of LIPR and IL6ST) and type II OSM receptor (heterodimers composed of OSMR and IL6ST), and is involved in the maturation of fetal hepatocytes, thereby promoting liver development and regeneration. This protein is being studied for its involvement in several diseases and disorders including arterial occlusive disease, peripheral arterial occlusive disease, leukemia, kaposi's sarcoma, abdominal aortic aneurysm, status epilepticus, primary cutaneous amyloidosis, aortic aneurysm, bullous pemphigoid, neonatal jaundice, cutaneous malignant melanoma, plasmacytoma, systemic mastocytosis, mastocytosis, cervical squamous cell carcinoma, systemic lupus erythematosus, allergic rhinitis, squamous cell carcinoma, and lupus erythematosus. The protein has been linked to immune response IL-3 activation and signaling pathway, immune response oncostatin M signaling via JAK-Stat in human cells, development thrombopoetin signaling via JAK-STAT pathway, immune response Oncostatin M signaling via MAPK in human cells, MAPK signaling, endothelin-1 signaling pathway, molecular mechanisms of cancer, antioxidant action of vitamin-C, and Rho Family GTPases pathways where it interacts with IL6ST, TNNT1, LIFR, COL4A4, and COL4A6.

Bioinformatics

Uniprot Human
Human
Human
Human
Human
Mouse
Product By Gene ID 5008
Alternate Names
  • MGC20461
  • oncostatin M
  • oncostatin-M

Research Areas for Oncostatin M/OSM

Find related products by research area and learn more about each of the different research areas below.

Cell Cycle and Replication