NNT Products

Description

NNT encodes an integral protein of the inner mitochondrial membrane. The enzyme couples hydride transfer between NAD(H) and NADP(+) to proton translocation across the inner mitochondrial membrane. Under most physiological conditions, the enzyme uses energy from the mitochondrial proton gradient to produce high concentrations of NADPH. The resulting NADPH is used for biosynthesis and in free radical detoxification. Two alternatively spliced variants, encoding the same protein, have been found for this gene.

Bioinformatics

Uniprot	AAH32370 Human NM_012343 Human NP_892022 Human Q13423 Human
Product By Gene ID	23530
Alternate Names	MGC126502 mitochondrial nicotinamide nucleotide transhydrogenaseMGC126503 Pyridine nucleotide transhydrogenase