Ghrelin Products

Description

Ghrelin is an endogenous ligand for the growth hormone secretagogue receptor (GHSR; MIM 601898) and is involved in regulating growth hormone (GH; MIM 139250) release. Ghrelin is derived from a preprohormone called preproghrelin, which also generates a second peptide called obestatin. Obestatin is an endogenous ligand for the orphan G protein-coupled receptor GPR39 (MIM 602886) and is involved in satiety and decreased food intake.

Bioinformatics

Entrez	51738 Human
Uniprot	NP_057446.1 Human
Product By Gene ID	51738
Alternate Names	appetite-regulating hormone ghrelin ghrelin/obestatin preprohormone ghrelin/obestatin prepropeptide Growth hormone secretagogue Growth hormone-releasing peptide Motilin-related peptide MTLRPgrowth hormone secretagogue receptor ligand obestatin Protein M46

Related Ghrelin Blog Posts

Check out the latest blog posts on Ghrelin.

Appetite and Energy: A Ghrelin Balancing Act Ghrelin is the only potent orexigenic peptide in circulation. It stimulates food intake and leads to metabolism regulation, positive energy balance, adipogenesis, and body weight gain. However, in studies using ghrelin antibodies, the physiological si...    Read more.

Shades of Ghrelin in Weight Homeostasis The neuropeptide and gut hormone Ghrelin is an endogenous ligand for the growth hormone (GH)-secretagogue receptor (GHSR) within the central nervous system. This pathway has received a great deal of attention and heavy study within the last decade bec...    Read more.

Ghrelin: Targeting the Hunger Hormone to Combat Obesity and Type 2 Diabetes As the hormone ghrelin is linked to appetite and weight gain, as well as impaired glucose-induced insulin secretion, there is considerable interest in this peptide as a potential drug target. Although the overall lack of success in this field has been...    Read more.

Read more Ghrelin related blogs.