Species: Hu, Mu, Rt, Po, Ca
Applications: WB, ICC/IF, IHC, KD
Host: Rabbit Polyclonal
Species: Hu
Applications: ELISA
Species: Hu
Applications: ELISA
Description
Dual oxidase 2 (DUOX2), a reduced NAD phosphate:O2 oxidoreductase flavoprotein, plays a critical role in the synthesis of thyroid hormones by providing thyroperoxidase with hydrogen peroxide, which is required for hormone synthesis at the apical plasma membrane. The discovery of DUOX-2 as a novel source of hydrogen peroxide in the digestive tract, particularly in the cecum and colon, makes it a new candidate mediator of physiopathological processes.
DUOX2 antibodies may be useful tools for thyroid hormone synthesis, hormonal regulation disorders, and certian types of cancer.
Bioinformatics
Entrez |
Human Rat Mouse |
Uniprot |
Human |
Product By Gene ID |
50506 |
Alternate Names |
- dual oxidase 2
- dual oxidase-like domains 2
- EC 1.11.1.-
- EC 1.6.3.1
- flavoprotein NADPH oxidase
- Large NOX 2
- LNOX2P138(TOX)
- Long NOX 2
- NADH/NADPH thyroid oxidase p138-tox
- NADPH oxidase/peroxidase DUOX2
- NADPH thyroid oxidase 2
- nicotinamide adenine dinucleotide phosphate oxidase
- NOXEF2
- p138 thyroid oxidase
- P138-TOX
- THOX2TDH6
- Thyroid oxidase 2
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