DNASE1 Products

Description

DNASE1, also known as Deoxyribonuclease 1, is an endonuclease found in the zymogen granules of the nuclear envelope. Responsible for DNA fragmentation and cell death during apoptosis, DNASE1 binds to G-actin and blocks actin polymerization. Mutations in DNASE1 cause systemic lupus erythematosus (SLE), an autoimmune disease causing inflammation and tissue damage. DNASE1 is also known to treat symptoms of cystic fibrosis.

Bioinformatics

Entrez	1773 Human 282217 Bovine
Uniprot	NM_005223 Human NP_005214 Human NP_005214.2 Human P24855 Human
Product By Gene ID	1773
Alternate Names	deoxyribonuclease IFLJ38093 deoxyribonuclease-1 DKFZp686H0155 DNase I DNase I, lysosomal DNL1FLJ44902 Dornase alfa DRNI EC 3.1.21.1 human urine deoxyribonuclease I

Research Areas for DNASE1

Find related products by research area and learn more about each of the different research areas below.

Apoptosis
DNA Repair
DNA replication, Transcription, Translation and Splicing