Species: Hu, Rt, Ze, Xp
Applications: WB, ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu, Mu
Applications: WB, IHC, IP
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt
Applications: WB, IHC, KD
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Species: Hu
Applications: AC
Description
DLST, also known as Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, is a 48.8 kDa, 453 amino acid protein that is involved in catalyzing the reaction of 2-oxoglutarate into succinyl-CoA and carbon dioxide. Current research is investigating the effect of the protein on malaria, neurodegeneration, pneumonia, cat-scratch disease, ataxia, prostatitis, Parkinson's disease, and Alzheimer's disease. The protein is involved in lysine degradation, citric acid cycle (TCA cycle), and metabolism pathways where it interacts with FLII, ATP6V1B2, HSPD1, UMPS, and DDOST.
Bioinformatics
Entrez |
Human |
Uniprot |
Human Human |
Product By Gene ID |
1743 |
Alternate Names |
- 2-oxoglutarate dehydrogenase complex component E2
- dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutaratecomplex)
- Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenasecomplex
- dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutaratedehydrogenase complex, mitochondrial
- DLTS
- E2K
- EC 2.3.1
- EC 2.3.1.61
- OGDC-E2
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