CD30/TNFRSF8 Products

Description

CD30 is a type I transmembrane protein and a member of the tumor necrosis factor receptor superfamily of proteins. (1,2) Murine CD30 is expressed predominantly in the thymus, and it is inducible in mouse splenocytes stimulated with pokeweed mitogen or concanavalin A. (1) In anti-CD3epsilon-activated spleen cells, CD30 is expressed primarily on the surface of CD8+ T cells with peak expression on days 4 and 5. Stimulation of CD30+ CTL lines with plate-bound anti-CD30 directly signals IL-5 but not IFN; production. (1) While these studies demonstrate that CD30 directs cytokine secretion and suggest that CD30 may play a pivotal role in the pattern of cytokine production by T cells, the precise roles of CD30 and its ligand (CD153) in T-cell development have not been clearly defined.

Bioinformatics

Entrez	21941 Mouse 943 Human
Uniprot	NM_001243 Human NP_001234 Human P28908 Human Q60846 Mouse
Product By Gene ID	943
Alternate Names	CD30 antigen CD30 CD30KI-1 CD30L receptor cytokine receptor CD30 D1S166EKi-1 Ki-1 antigen Lymphocyte activation antigen CD30 tumor necrosis factor receptor superfamily member 8 tumor necrosis factor receptor superfamily, member 8

Research Areas for CD30/TNFRSF8

Find related products by research area and learn more about each of the different research areas below.

Apoptosis
Cell Cycle and Replication
Embryonic Stem Cell Markers
Immunology
Stem Cell Markers

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