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CCM2 Products

Antibodies
Lysates
CCM2 Overexpression Lysate
CCM2 Overexpression Lysate
NBL1-08862
Species: Hu
Applications: WB
Proteins
Recombinant Human CCM2 His Pr ...
Recombinant Human CCM2 His Protein
NBP2-22769
Species: Hu
Applications: PAGE
CCM2 Recombinant Protein Anti ...
CCM2 Recombinant Protein Antigen
NBP1-86729PEP
Species: Hu
Applications: AC
CCM2 Recombinant Protein Anti ...
CCM2 Recombinant Protein Antigen
NBP1-86730PEP
Species: Hu
Applications: AC

Description

p16 INK4a is a tumor suppressor protein. It is a specific inhibitor of Cdk 4 / Cdk 6, and a tumor suppressor involved in the pathogenesis of a variety of malignancies. Recent analyses of the p16 INK4a gene revealed homozygous deletions, nonsense, missense, or frameshift mutations in several human cancers. Although the frequency of p16 INK4a abnormalities is higher in tumor derived cell lines than in unselected primary tumors, significant subsets of clinical cases with aberrant p16 INK4a gene have been reported among melanomas, gliomas, esophageal, pancreatic, lung, and urinary bladder carcinomas, and some types of leukemia.

Bioinformatics

Entrez Mouse
Human
Uniprot Human
Human
Human
Human
Human
Product By Gene ID 83605
Alternate Names
  • C7orf22OSM
  • cerebral cavernous malformation 2
  • Cerebral cavernous malformations 2 protein
  • chromosome 7 open reading frame 22
  • malcavernin
  • MGC4067
  • MGC4607
  • MGC74868