Cathepsin C/DPPI Products

Description

DPP1 is encoded by this gene, a member of the peptidase C1 family, is a lysosomal cysteine proteinase that appears to be a central coordinator for activation of many serine proteinases in immune/inflammatory cells. It is composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor, and a residual portion of the propeptide acts as an intramolecular chaperone for the folding and stabilization of the mature enzyme. This enzyme requires chloride ions for activity and can degrade glucagon. Defects in the encoded protein have been shown to be a cause of Papillon-Lefevre syndrome, an autosomal recessive disorder characterized by palmoplantar keratosis and periodontitis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Bioinformatics

Entrez	1075 Human
Uniprot	NM_001814.4 Human NP_001805 Human P53634 Human
Product By Gene ID	1075
Alternate Names	cathepsin CEC 3.4.14.1 Cathepsin J CPPIHMS dipeptidyl peptidase 1 Dipeptidyl peptidase I Dipeptidyl transferase dipeptidyl-peptidase I DPP1 DPPI DPP-I JP JPD PALS PLS

Research Areas for Cathepsin C/DPPI

Find related products by research area and learn more about each of the different research areas below.

Core ESC-Like Genes
Stem Cell Markers