Species: Hu
Applications: ELISA, IHC
Host: Sheep Polyclonal
Species: Hu
Applications: WB, ELISA, IHC
Host: Goat Polyclonal
Species: Hu, Mu, Rt
Applications: WB, ELISA, ICC/IF
Host: Rabbit Polyclonal
Species: Hu
Applications: ELISA
Species: Hu
Applications: WB
Species: Hu
Applications: WB, ELISA, MA, AP
Species: Hu
Applications: AC
Description
Defensins are a family of microbicidal and cytotoxic peptides thought to be involved in host defense. They are abundantin the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine,respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequenceand distinguished by a conserved cysteine motif. Several alpha defensin genes appear to be clustered on chromosome 8.The protein encoded by this gene, defensin, alpha 1, is found in the microbicidal granules of neutrophils and likelyplays a role in phagocyte-mediated host defense. It differs from defensin, alpha 3 by only one amino acid. (providedby RefSeq)
Bioinformatics
| Entrez |
Human
|
| Uniprot |
Human
Human
Human
Human
|
| Product By Gene ID |
1667 |
| Alternate Names |
- alpha 2
- DEF1DEFA1B
- DEFA2
- defensin, alpha 1, myeloid-related sequence
- defensin, alpha 1HP-1
- HNP-1HP1
- MRSMGC138393
- myeloid-related sequence
- neutrophil defensin 1
|
Research Areas for alpha-Defensin 1
Find related products by research area and learn more about each of the different research areas below.
ApoptosisCancerSignal Transduction
![Immunohistochemistry alpha-Defensin 1 Antibody [Unconjugated]](http://images.novusbio.com/fullsize2/alphaDefensin_1_AF8198_Immunohistochemistry_14549.jpg)
![ELISA alpha-Defensin 1 Antibody [Unconjugated]](http://images.novusbio.com/fullsize2/alphaDefensin_1_AF8198_ELISA_22234.jpg)
![N/A alpha-Defensin 1 [Biotin]](http://images.novusbio.com/fullsize2/DATA_alphaDefensin_1_DY819805_ELISA_2534.jpg)
