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parp antibody

Caspase 7: The Cell's Suicide Switch

Caspase 7 (also known as CASP7, Mch3, ICE-LAP3, CMH-1) is a member of caspase family of cysteine proteases. It is an apoptosis-related cystein peptidase encoded by the CASP7 gene in humans. CASP7 homologous sequences have been identified in nearly all mammals. Similar to Caspase 3, Caspase-7 is an effector caspase and plays a key role in apoptotic execution.

PARP Antibody Assays aid both Apoptosis and Cancer Research

The PARP (Poly(ADP-ribose) polymerase) protein is a zinc-dependant nuclear enzyme whose main role is to detect and repair DNA single-strand breaks (SSB). However, PARP antibody research has revealed there are at least 17 PARP proteins, which also play a major role in apoptosis (programmed cell death) and post-translational modification. We at Novus Biologicals have an extensive range of PARP antibody products in our antibody catalogu.