The low density lipoprotein receptor coordinates the metabolism of cholesterol, an essential component of the mammalian cell plasma membranes. Study of this carefully balanced system has led to an enhanced understanding of cholesterol homeostasis at the cellular level. Receptor-mediated endocytosis (RME) is an important mechanism of metabolic regulation.
The low density lipoprotein receptor coordinates the metabolism of cholesterol, an essential component of the mammalian cell plasma membranes. Study of this carefully balanced system has led to an enhanced understanding of cholesterol homeostasis at the cellular level. Receptor-mediated endocytosis (RME) is an important mechanism of metabolic regulation.
