Sorting Nexin Family Member 27 (SNX27) binds the cell membrane to regulate endocytic vesicular and protein trafficking. SNX27 has also been shown to play a key role in the endocytic recycling pathway, whereby internalized membrane proteins and lipids are degraded and recycled into the cell, in T lymphocytes. In their groundbreaking work on endocytic recycling pathways, Dr. F Maxfield and Dr. T McGraw showed that these pathways are essential for proper organelle maintenance and homeostatic regulation of molecules.
