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Stem Cells

Successful Transplantation of Friedreich Ataxia Induced Pluripotent Stem Cell (iPSC)-Derived Sensory Neurons in Dorsal Root Ganglia of Adult Rodents

Transcriptional co-activators Yap1 and Taz control growth and development

Breast cancer stem cells survive chemotherapy through S100A10-ANXA2-SPT6 interaction that epigenetically promotes OCT4-mediated stemness

Antibody treatment can generate microglia-like cells from bone marrow

Deriving neural precursor cells from human induced pluripotent stem cells

Stemness is responsible for onset and metastasis of colorectal cancer

Flow Cytometry Basics for the Non-Expert

Meeting Report: 2nd International Antibody Validation Meeting

Bio-Techne brands Novus Biologicals® and R&D Systems® were proud to support the 2nd International Antibody Validation Meeting held at Bath University, on the 15-16 September, 2016. Almost 100 participants from around the world, including funders, publishers, academics, pharma and antibody manufacturers were in attendance, to share and discuss best practices in research antibody validation and to drive improved antibody validation standards for the global life science community.

Beta Tubulin III and neurogenesis

Beta tubulin III, also known as Tuj-1, is a class III member of the beta tubulin protein family. Beta tubulins are one of two structural components that form our microtubule network.

Beta III tubulin

The Beta III tubulin protein is abundantly present in both the central and peripheral nervous systems (CNS and PNS), where it is predominantly expressed during fetal and postnatal development. In cerebellar and sympathoadrenal neurogenesis, Beta III distribution is neuron-associated and present in distinct temporal-spatial gradients that are dictated by the regional neuroepithelia of origin.

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