Complexin-2 Antibody [Unconjugated]

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Complexin-2 (CPX II; also known as synaphin-1) is a 19 kDa, cytosolic protein that belongs to the complexin/synaphin family of molecules. It is expressed in excitatory neurons and serves as a block against premature granule release by its binding to the cis-SNARE complex that contains SNAP25, VAMP2 and STX1A. Human Complexin-2 is 134 amino acids (aa) in length and contains one coiled-coil domain (aa 28‑84) that incorporates part of a SNARE complex interaction sequence (aa 41‑97). There is one potential splice variant that shows a premature truncation after Glu114. Human Complexin-2 is identical in aa sequence to that for mouse and rat Complexin-2.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publication using AF5085	Applications	Species
Yeli Zhou, Jing Li, Feng Xu, Encheng Ji, Chenglong Wang, Zheer Pan Long noncoding RNA H19 alleviates inflammation in osteoarthritis through interactions between TP53, IL-38, and IL-36 receptor Bone & Joint Research 2022-08-17 [PMID: 35942891]

Array AF5085

• Complexin-2 Antibodies
• Complexin-2 ELISA Kits
• Complexin-2 Lysates
• Complexin-2 Protein