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TRAILR3/TNFRSF10C Antibody (90906) [Janelia Fluor® 549]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, CyTOF-ready
Clone
90906
Clonality
Monoclonal
Host
Mouse
Conjugate
Janelia Fluor 549

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB6302U-100UG
Alexa Fluor 405
FAB6302V-100UG
Alexa Fluor 488
FAB6302G-100UG
Alexa Fluor 532
FAB6302X
Alexa Fluor 594
FAB6302T-100UG
Alexa Fluor 647
FAB6302R-100UG
Alexa Fluor 700
FAB6302N-100UG
Alexa Fluor 750
FAB6302S-100UG
Allophycocyanin
FAB6302A
Allophycocyanin/Cy7
FAB6302APCCY7
Biotin
FAB6302B
DyLight 350
FAB6302D
DyLight 405
FAB6302E
DyLight 488
FAB6302K
DyLight 550
FAB6302L
DyLight 594
FAB6302M
DyLight 650
FAB6302W
DyLight 680
FAB6302Y
DyLight 755
FAB6302Z
FITC
FAB6302F
HRP
FAB6302H
Janelia Fluor 525
FAB6302JF525
Janelia Fluor 585
FAB6302JF585
Janelia Fluor 635
FAB6302JF635
Janelia Fluor 646
FAB6302J
Janelia Fluor 669
FAB6302JF669
PE/Atto594
FAB6302PEATT594
PE/Cy5.5
FAB6302PECY55
PE/Cy7
FAB6302PECY7
PerCP
FAB6302C
Unconjugated
MAB6302
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB6302
Carrier Free
FAB6302A
Carrier Free
MAB6302
Carrier Free
MAB6302-SP
Carrier Free
FAB6302V-100UG
Carrier Free
FAB6302U-100UG
Carrier Free
FAB6302T-100UG
Carrier Free
FAB6302S-100UG
Carrier Free
FAB6302R-100UG
Carrier Free
FAB6302N-100UG
Carrier Free
FAB6302G-100UG
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TRAILR3/TNFRSF10C Antibody (90906) [Janelia Fluor® 549] Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant human TRAIL R3/TNFRSF10C
Met1-Ala221
Accession # O14798
Specificity
Detects human TRAIL R3/TNFRSF10C in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant human (rh) TRAIL R2, rhTRAIL R1, or rhTRAIL R4 is observed.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
TNFRSF10C
Purity
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
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Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

0

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified from hybridoma culture supernatant

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for TRAILR3/TNFRSF10C Antibody (90906) [Janelia Fluor® 549]

  • Antagonist decoy receptor for TRAIL/Apo-2L
  • CD263 antigen
  • CD263
  • cytotoxic TRAIL receptor-3
  • DcR1
  • DCR1MGC149502
  • Decoy receptor 1
  • Decoy TRAIL receptor without death domain
  • LITMGC149501
  • Lymphocyte inhibitor of TRAIL
  • TNFRSF10C
  • TRAIL R3
  • TRAIL receptor 3
  • TRAIL receptor without an intracellular domain
  • TRAILR3
  • TRAIL-R3
  • TRAILR3TNF-related apoptosis-inducing ligand receptor 3
  • TRIDDCR1-TNFR
  • tumor necrosis factor receptor superfamily member 10C
  • tumor necrosis factor receptor superfamily, member 10c, decoy without anintracellular domain

Background

DcR1 / TRAIL-R3 / TRID / LIT is one of the two putative decoy receptors identified for TRAIL, one of the members of TNF family of apoptosis inducing proteins. The other putative decoy receptor is called DcR2 / TRUNDD / TRAIL-R4. DcR1 is attached to the cell surface through glycophospholipid anchor. It has the extracellular TRAIL binding domain but lacks the cytoplasmic domain to induce apoptotic signal. Hence overexpression of DcR1 inhibits the TRAIL induced apoptosis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol TNFRSF10C