TP53INP2 Antibody [FITC]

This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Tumor protein p53 inducible nuclear protein 2 is necessary for tumor cell invasive migration. Different splicing events in formation of this protein are key determinants of whether the tumor cell invasive morphology exists, and is probably mediated through a Golgi complex interaction. TP53INP2 also binds the Atg8-like proteins and VMP1 during autophagy, and generates scaffolding for autophagosome membranes. LC3 and LC3R also interact with TP53INP2 through an interaction with the autophagosome transmembrane protein VMP1. Thus, the effect of TP53INP2 on tumor growth seems to be both a direct effect on invasion and an indirect effect of insufficient autophagosome scaffolding and inflammation events in response to tumor formation.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Array NBP1-71704F

• TP53INP2 Antibodies