Thymidylate Synthase Antibody (rTYMS/1884) [HRP]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA, Flow, ICC/IF
Clone
rTYMS/1884
Clonality
Monoclonal
Host
Mouse
Conjugate
HRP

Order Details

Thymidylate Synthase Antibody (rTYMS/1884) [HRP] Summary

Additional Information
Recombinant Monoclonal Antibody
Immunogen
Recombinant human thymidylate synthase protein fragment (around aa 60-174) (exact sequence is proprietary) (Uniprot: P04818)
Localization
Nuclear & Cytoplasmic
Marker
5-FU Resistance Marker
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
TYMS
Purity
Protein A or G purified
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Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA
  • Flow Cytometry
  • Immunocytochemistry/ Immunofluorescence
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
No Preservative
Purity
Protein A or G purified

Alternate Names for Thymidylate Synthase Antibody (rTYMS/1884) [HRP]

  • EC 2.1.1.45
  • HsT422
  • MGC88736
  • OK/SW-cl.29
  • Thymidylate Synthase
  • thymidylate synthetase
  • TMSTsase
  • TS
  • TSase
  • TSHST422
  • TYMS

Background

Thymidylate synthase (TS) is an intracellular enzyme critical for de novo synthesis of DNA. In cancer, expression of TS is often elevated and becomes further elevated as a result of treatment with the most commonly used chemotherapeutic, 5-fluorouracil (5-FU). Resistance or lack of response to 5-FU is attributed to the elevation of TS activity. Overexpression of TS has been demonstrated in many types of tumors including breast, colon, gastric and melanoma and is usually predictive of shortened survival time.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Thymidylate Synthase Antibody (NBP3-08887H) (0)

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Product General Protocols

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Video Protocols

ICC/IF Video Protocol

FAQs for Thymidylate Synthase Antibody (NBP3-08887H) (0)

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Bioinformatics

Gene Symbol TYMS