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TCP1-beta Antibody (F39 P7 F11)

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Immunohistochemistry: TCP1-beta Antibody (F39 P7 F11) [NBP2-66591]
Immunohistochemistry: TCP1-beta Antibody (F39 P7 F11) [NBP2-66591]

Product Details

Summary
Reactivity Hu, Mu, Rt, XpSpecies Glossary
Applications WB, IHC
Clone
F39 P7 F11
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

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TCP1-beta Antibody (F39 P7 F11) Summary

Immunogen
Hybridoma produced by the fusion of splenocytes from BALB/c mice immunized with a synthetic peptide derived from the C-terminal of the TCP1-beta protein (Uniprot: P47207) and mouse myeloma Ag8563 cells.
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
CCT2
Purity
Protein A or G purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Immunohistochemistry 5-10 ug/ml
  • Immunohistochemistry-Paraffin 1-5 ug/ml
  • Western Blot 1-2 ug/ml

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.08% Sodium Azide
Purity
Protein A or G purified

Alternate Names for TCP1-beta Antibody (F39 P7 F11)

  • Cctb
  • CCT-beta
  • CCTBPRO1633,99D8.1
  • chaperonin containing t-complex polypeptide 1, beta subunit
  • chaperonin containing t-complex polypeptide 1, subunit 2
  • chaperonin containing TCP1, subunit 2 (beta)
  • MGC142074
  • MGC142076
  • T-complex protein 1 subunit beta
  • T-complex protein 1, beta subunit
  • TCP-1-beta

Background

The protein TCP-1 (t-complex polypeptide 1) is a subunit of the hetero-oligomeric complex CCT (chaperonin containing TCP-1) present in the eukaryotic cytosol. The CCT of eukaryotic cytosol is composed of eight different subunit species that are proposed to have independent functions in folding its in vivo substrates, the Actins and Tubulins. TCP-1 was first identified in the mouse as relevant for tail-less and embryonic lethal phenotypes. Sequences homologous to TCP-1 have been isolated in several other species, and the yeast TCP-1 has been shown to encode a molecular chaperone for Actin and Tubulin. TCP-1 found in mammalian cells and yeast plays an important role in the folding of cytosolic proteins.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol CCT2
Uniprot