Recombinant Human SPOP His Protein

SPOP (speckle-type POZ protein), also known as TEF2, is a member of the Tdpoz family containing one N-terminal MATH (Meprin and TRAF homology) domain and one C-terminal BTB/POZ domain. This protein inhibits IPF1/PDX1 transactivation of established target promoters, such as insulin, may be by recruiting a repressor complex. Through an interaction with CUL-3, SPOP is involved in ubiquitinylation and protein degradation. Recombinant human SPOP protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

We have publications tested in 1 application: PAGE.

Showing Publication 1 - 1 of 1.

Publication using NBP1-51077	Applications	Species
Mukhopadhyay C, Yang C, Xu L Et al. G3BP1 inhibits Cul3SPOP to amplify AR signaling and promote prostate cancer Nature communications 2021-11-18 [PMID: 34795264] (PAGE)	PAGE

Array NBP1-51077

• SPOP Antibodies
• SPOP Lysates
• SPOP Protein