Serpin B5/Maspin Antibody (SERPINB5/4977) [DyLight 680]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC, MA
Clone
SERPINB5/4977
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 680

Order Details

Serpin B5/Maspin Antibody (SERPINB5/4977) [DyLight 680] Summary

Immunogen
Recombinant fragment of human Serpin B5/Maspin protein (around aa1-200) (exact sequence is proprietary) (Uniprot: P36952)
Localization
Secreted, Extracellular space
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
SERPINB5
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry-Paraffin
  • Protein Array
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

0

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for Serpin B5/Maspin Antibody (SERPINB5/4977) [DyLight 680]

  • Maspin
  • Peptidase inhibitor 5
  • PI5
  • PI-5
  • PI5protease inhibitor 5 (maspin)
  • serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 5
  • Serpin B5
  • serpin peptidase inhibitor, clade B (ovalbumin), member 5

Background

Maspin is an extracellular matrix tumor supressor that blocks the growth, invasion, and metastatic properties of mammary and prostate tumors. Structurally Maspin is a serine protease inhibitor (Serpin), but it does not undergo the stressed to relaxed conformational transition characteristic of active serpins and exhibits no serine protease inhibitory activity. Maspin is also expressed by the corneal epithelium and regulates migration and adhesion of corneal stromal fibroblasts and myofibroblasts during corneal wound healing.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

FAQs for Serpin B5/Maspin Antibody (NBP3-14137FR) (0)

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol SERPINB5