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Red Blood Cells Antibody (34-3C)

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications Flow, Func
Clone
34-3C
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
0.1 mg/ml

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Red Blood Cells Antibody (34-3C) Summary

Immunogen
RBC
Epitope
The monoclonal antibody 34-3C recognizes an exposed surface determinant of intact red blood cells (RBC).
Specificity
The monoclonal antibody only recognises antigenic determinants expressed on Mouse RBC and not on other species of RBC.
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Purity
Protein G purified
Endotoxin Note
<24 EU/mg
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry
  • Functional
Application Notes
For Flow Cytometry dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:50. For functional studies, in vitro dilutions have to be optimized in user's experimental setting.

Packaging, Storage & Formulations

Storage
Store at 4C.
Buffer
0.2 um filtered solution in PBS, 0.1% BSA
Preservative
No Preservative
Concentration
0.1 mg/ml
Purity
Protein G purified

Alternate Names for Red Blood Cells Antibody (34-3C)

  • Erythrocytes
  • Erythroid Cells
  • Haematids
  • RBC

Background

The monoclonal antibody 34-3C recognizes an exposed surface determinant of intact red blood cells (RBC). The high-affinity anti-RBC monoclonal antibody efficiently bind to Fc receptors on macrophages inducing anemia in vivo due to a rapid Fc receptor (FcyR)-mediated erythrophagocytosis of opsonised RBC in spleen and livers. The capacity of the antibody to interact with FcyR is responsible for its haemolytic activity. The monoclonal antibody only recognises antigenic determinants expressed on Mouse RBC and not on other species of RBC.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

Additional Red Blood Cells Products

Array NBP3-11200

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