PAX8 Antibody (PAX8/6848R) [DyLight 488]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clone
PAX8/6848R
Clonality
Monoclonal
Host
Rabbit
Conjugate
DyLight 488

Order Details

PAX8 Antibody (PAX8/6848R) [DyLight 488] Summary

Additional Information
Recombinant Monoclonal Antibody
Immunogen
Recombinant fragment (around aa150-300) of human PAX8 (exact sequence is proprietary)
Localization
Nucleus.
Marker
Renal Cell Marker
Isotype
IgG Kappa
Clonality
Monoclonal
Host
Rabbit
Gene
PAX8
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry-Paraffin
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for PAX8 Antibody (PAX8/6848R) [DyLight 488]

  • paired box 8
  • paired box gene 8
  • paired box protein Pax-8
  • paired domain gene 8

Background

PAX8 is a member of the paired box (PAX) family of transcription factors, typically containing a paired box domain, an octapeptide, and a paired-type homeodomain. This family plays critical roles during fetal development and cancer growth. The specific function of the PAX8 is unknown but it may involve kidney cell differentiation, thyroid development, or thyroid dysgenesis. Alternative splicing in the gene by inclusion or exclusion of exons 7 and/or 8 has produced several known products but the biological significance of the variants is unknown. Several other splice variants have been proposed but the full nature of these products has not been described.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Secondary Antibodies

 

Isotype Controls

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Research Areas for PAX8 Antibody (NBP3-24166G)

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Blogs on PAX8

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Bioinformatics

Gene Symbol PAX8