Oval Cell Marker Antibody (MIC1-1C3) [mFluor Violet 610 SE] Summary
| Immunogen |
Nonparenchymal cells from DDC-treated mice |
| Specificity |
Specific for hepatic proliferating duct cells. |
| Isotype |
IgG2a |
| Clonality |
Monoclonal |
| Host |
Rat |
| Purity |
Protein G purified |
| Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
| Dilutions |
- CyTOF-ready
- Flow Cytometry
- Immunocytochemistry/ Immunofluorescence
- Immunohistochemistry
- Immunohistochemistry-Frozen
- Immunohistochemistry-Paraffin
|
| Application Notes |
Optimal dilution of this antibody should be experimentally determined. |
Reactivity Notes
Human reactivity reported in scientific literature (PMID: 30236451).
Packaging, Storage & Formulations
| Storage |
Store at 4C in the dark. |
| Buffer |
50mM Sodium Borate |
| Preservative |
0.05% Sodium Azide |
| Purity |
Protein G purified |
Notes
mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.
Background
Facultative liver stem cell activation was originally described in the rat, where chemical damage and partial hepatectomy caused the emergence of a new cell type, the oval cell. These cells are thought to be bipotential progenitors capable of yielding both hepatocytes and bile ducts (1). To properly determine the molecular regulation of the progenitor process, appropriate markers are needed to identify and isolate cells that emerge during the oval cell response.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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Product General Protocols
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Video Protocols
FAQs for Oval Cell Marker Antibody (NBP1-18961MFV610) (0)
Secondary Antibodies
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Isotype Controls
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Additional Oval Cell Marker Products
Blogs on Oval Cell Marker
![Oval Cell Marker Antibody (MIC1-1C3) [mFluor Violet 610 SE] [NBP1-18961MFV610] - Vial of mFluor Violet 610 conjugated antibody. mFluor Violet 610 is optimally excited at 421 nm by the Violet laser (405 nm) and has an emission maximum of 613 nm.](http://images.novusbio.com/fullsize/nbp1-18961mfv610_rat-oval-cell-marker-mab-mic1-1c3-mfluor-violet-610-se-672023924424.png "Oval Cell Marker Antibody (MIC1-1C3) [mFluor Violet 610 SE] [NBP1-18961MFV610] - Vial of mFluor Violet 610 conjugated antibody. mFluor Violet 610 is optimally excited at 421 nm by the Violet laser (405 nm) and has an emission maximum of 613 nm.")
