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Oval Cell Marker Antibody (MIC1-1C3) [Janelia Fluor® 646]

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Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications Flow, ICC/IF, IHC, CyTOF-ready
Clone
MIC1-1C3
Clonality
Monoclonal
Host
Rat
Conjugate
Janelia Fluor 646

Order Details

Oval Cell Marker Antibody (MIC1-1C3) [Janelia Fluor® 646] Summary

Immunogen
Nonparenchymal cells from DDC-treated mice
Localization
Cell surface
Marker
Hepatic periductal cell Marker
Specificity
Specific for hepatic proliferating duct cells.
Isotype
IgG2a
Clonality
Monoclonal
Host
Rat
Purity
Protein G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Frozen
  • Immunohistochemistry-Paraffin
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Human reactivity reported in scientific literature (PMID: 30236451).

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein G purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Background

Facultative liver stem cell activation was originally described in the rat, where chemical damage and partial hepatectomy caused the emergence of a new cell type, the oval cell. These cells are thought to be bipotential progenitors capable of yielding both hepatocytes and bile ducts (1). To properly determine the molecular regulation of the progenitor process, appropriate markers are needed to identify and isolate cells that emerge during the oval cell response.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Oval Cell Marker Antibody (NBP1-18961JF646) (0)

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Product General Protocols

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Video Protocols

ICC/IF Video Protocol

FAQs for Oval Cell Marker Antibody (NBP1-18961JF646) (0)

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Secondary Antibodies

 

Isotype Controls

Additional Oval Cell Marker Products

Array NBP1-18961JF646

Research Areas for Oval Cell Marker Antibody (NBP1-18961JF646)

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mFluor Violet Conjugated Antibodies

Contact Information

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Calculators

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