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Nectin-2/CD112 Antibody (610603) [DyLight 680]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, ICC/IF
Clone
610603
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 680

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB2229U-100UG
Alexa Fluor 405
FAB2229V-100UG
Alexa Fluor 488
FAB2229G
Alexa Fluor 532
FAB2229X
Alexa Fluor 594
FAB2229T-100UG
Alexa Fluor 647
FAB2229R-100UG
Alexa Fluor 700
FAB2229N
Alexa Fluor 750
FAB2229S-100UG
Allophycocyanin
FAB2229A
Allophycocyanin/Cy7
FAB2229APCCY7
Biotin
FAB2229B
CoraFluor 1
FAB2229CL1
DyLight 350
FAB2229D
DyLight 405
FAB2229E
DyLight 488
FAB2229K
DyLight 550
FAB2229L
DyLight 594
FAB2229M
DyLight 650
FAB2229W
DyLight 755
FAB2229Z
FITC
FAB2229F
HRP
FAB2229H
Janelia Fluor 525
FAB2229JF525
Janelia Fluor 549
FAB2229I
Janelia Fluor 585
FAB2229JF585
Janelia Fluor 635
FAB2229JF635
Janelia Fluor 646
FAB2229J
Janelia Fluor 669
FAB2229JF669
PerCP
FAB2229C
Unconjugated
MAB2229-100
mFluor Violet 450 SE
FAB2229MFV450
mFluor Violet 500 SE
FAB2229MFV500
mFluor Violet 610 SE
FAB2229MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB2229-100
Carrier Free
FAB2229A
Carrier Free
FAB2229G
Carrier Free
FAB2229N
Carrier Free
MAB2229-100
Carrier Free
MAB2229-SP
Carrier Free
FAB2229U-100UG
Carrier Free
FAB2229S-100UG
Carrier Free
FAB2229T-100UG
Carrier Free
FAB2229R-100UG
Carrier Free
FAB2229V-100UG
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Nectin-2/CD112 Antibody (610603) [DyLight 680] Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant human Nectin‑2/CD112
Gln32-Gly360
Accession # Q92692
Specificity
Detects human Nectin‑2/CD112 in direct ELISAs.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Purity
Protein A or G purified from hybridoma culture supernatant
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Applications/Dilutions

Dilutions
  • Flow Cytometry
  • Immunocytochemistry
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified from hybridoma culture supernatant

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for Nectin-2/CD112 Antibody (610603) [DyLight 680]

  • CD112 antigen
  • CD112
  • Herpes virus entry mediator B
  • Herpesvirus entry mediator B
  • herpesvirus entry protein B
  • HVEB
  • HVEBpoliovirus receptor-like 2
  • MPH
  • nectin 2
  • Nectin2
  • Nectin-2
  • poliovirus receptor-related 2 (herpesvirus entry mediator B)
  • poliovirus receptor-related protein 2
  • PRR2
  • PRR2nectin-2
  • PVRL2
  • PVRR2poliovirus receptor related 2

Background

Nectin 2 encodes a single-pass type I membrane glycoprotein with two Ig-like C2-type domains and an Ig-like V-type domain. This protein is one of the plasma membrane components of adherens junctions. It also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, and it is involved in cell to cell spreading of these viruses. Variations in this gene have been associated with differences in the severity of multiple sclerosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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