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MSH3 Antibody (CL14064)

Images

 
Staining of human endometrium shows moderate nuclear positivity in glandular and in stromal cells.
Western blot analysis in human cell line U-251 MG.
Staining of human cervical cancer shows strong nuclear positivity in tumor cells.
Staining of human kidney shows moderate nuclear positivity in cells in tubules and cells in glomeruli.
Staining of human cerebellum shows moderate nuclear positivity in Purkinje cells.
Staining of human colorectal cancer shows moderate to strong nuclear positivity in tumor cells.
Staining in RH-30 cell line with Anti-MSH3 monoclonal antibody, showing specific staining of nucleoplasm and nucleus and nucleoli in green. Microtubule- and nuclear probes are visualized in red and blue respectively ...read more
Staining of human breast cancer shows moderate to strong nuclear positivity in tumor cells.
Staining of human uterine cervix shows moderate nuclear positivity in squamous epithelial cells.
Staining of human testis shows no positivity in cells in seminiferous ducts.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ICC/IF, IHC
Clone
CL14064
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

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MSH3 Antibody (CL14064) Summary

Immunogen
This antibody was designed to target the recombinant protein MSH3, with the precise immunogen sequence being withheld for proprietary reasons.
Predicted Species
Mouse (100%), Rat (100%). Backed by our 100% Guarantee.
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
MSH3
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence 2-10 ug/ml
  • Immunohistochemistry 1:200 - 1:500
  • Immunohistochemistry-Paraffin 1:200 - 1:500
  • Western Blot 1ug/ml
Application Notes
For IHC-Paraffin, we recommend using Heat-Induced Epitope Retrieval (HIER) with a pH level of 6. This optimized retrieval method ensures the best results for your experiments, For ICC/IF, we recommend using a combination of PFA and Triton X-100. This will give you the optimal results for your experiments.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS, pH 7.2, 40% glycerol
Preservative
0.02% Sodium Azide
Purity
Protein A purified

Alternate Names for MSH3 Antibody (CL14064)

  • Divergent upstream protein
  • DNA mismatch repair protein Msh3
  • DUC1
  • DUG
  • DUPMGC163306
  • hMSH3
  • Mismatch repair protein 1
  • MRP1MGC163308
  • mutS (E. coli) homolog 3
  • mutS homolog 3 (E. coli)

Background

The function of MSH3 is unknown. It is probably a DNA-repair protein. Defects in MSH3 are a cause of susceptibility to endometrial cancer.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for MSH3 Antibody (NBP3-24588) (0)

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Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for MSH3 Antibody (NBP3-24588) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Secondary Antibodies

 

Isotype Controls

Additional MSH3 Products

Array NBP3-24588

Research Areas for MSH3 Antibody (NBP3-24588)

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Blogs on MSH3

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Contact Information

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Bioinformatics

Gene Symbol MSH3