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MSH2 Antibody (MSH2/2622) [Janelia Fluor® 525]

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Product Details

Summary
Reactivity Hu, CaSpecies Glossary
Applications WB, Flow, ICC/IF, IHC
Clone
MSH2/2622
Clonality
Monoclonal
Host
Mouse
Conjugate
Janelia Fluor 525

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP3-08957AF350
Alexa Fluor 405
NBP3-08957AF405
Alexa Fluor 488
NBP3-08957AF488
Alexa Fluor 532
NBP3-08957AF532
Alexa Fluor 594
NBP3-08957AF594
Alexa Fluor 647
NBP3-08957AF647
Alexa Fluor 700
NBP3-08957AF700
Alexa Fluor 750
NBP3-08957AF750
Allophycocyanin
NBP3-08957APC
Biotin
NBP3-08957B
CoraFluor 1
NBP3-08957CL1
DyLight 350
NBP3-08957UV
DyLight 405
NBP3-08957V
DyLight 488
NBP3-08957G
DyLight 550
NBP3-08957R
DyLight 594
NBP3-08957DL594
DyLight 650
NBP3-08957C
DyLight 680
NBP3-08957FR
DyLight 755
NBP3-08957IR
FITC
NBP3-08957F
HRP
NBP3-08957H
Janelia Fluor 549
NBP3-08957JF549
Janelia Fluor 646
NBP3-08957JF646
Janelia Fluor 669
NBP3-08957JF669
PE
NBP3-08957PE
PerCP
NBP3-08957PCP
Unconjugated
NBP3-07211-100ug
mFluor Violet 450 SE
NBP3-08957MFV450
mFluor Violet 500 SE
NBP3-08957MFV500
mFluor Violet 610 SE
NBP3-08957MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP3-07211-100ug
Azide and BSA Free
NBP3-08957
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MSH2 Antibody (MSH2/2622) [Janelia Fluor® 525] Summary

Immunogen
Recombinant fragment (around aa 327-427) of human MSH2 protein (exact sequence is proprietary) (Uniprot: IDP43246)
Localization
Nuclear
Marker
DNA Mismatch Repair Marker
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
MSH2
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
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Applications/Dilutions

Dilutions
  • Flow Cytometry
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for MSH2 Antibody (MSH2/2622) [Janelia Fluor® 525]

  • COCA1
  • DNA mismatch repair protein Msh2
  • FCC1
  • hMSH2
  • HNPCC
  • HNPCC1
  • HNPCC1mutS (E. coli) homolog 2 (colon cancer, nonpolyposis type 1)
  • LCFS2
  • MSH2
  • mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)
  • MutS protein homolog 2

Background

MSH2 was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol MSH2