Mouse IL-13 Culture Media Quantikine ELISA, 2 Plate

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Summary
Reactivity MuSpecies Glossary
Applications ELISA
Conjugate
HRP

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Mouse IL-13 Culture Media Quantikine ELISA, 2 Plate Summary

Background
The Quantikine Mouse IL-13 Immunoassay is a 4.5 hour solid phase ELISA designed to measure mouse IL-13 levels in cell culture supernates. It contains recombinant mouse IL-13 and antibodies raised against the recombinant factor. This immunoassay has been shown to quantitate the recombinant mouse IL-13 accurately. Results obtained using natural mouse IL-13 showed dose curves that were par...allel to the standard curves obtained using the Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values for natural mouse IL-13.
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Specificity
Natural and recombinant mouse IL-13
Inter-Assay
See PDF Datasheet for details
Intra-Assay
See PDF Datasheet for details
Spike Recovery
See PDF Datasheet for details
Sample Volume
See PDF Datasheet for details
Gene
Il13

Applications/Dilutions

Dilutions
  • ELISA
Application Notes
No significant interference observed with available related molecules.
Publications
Read Publications using
M1300CB in the following applications:

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Mouse IL-13 Culture Media Quantikine ELISA, 2 Plate

  • ALRHMGC116789
  • BHR1interleukin-13
  • IL13
  • IL-13
  • IL-13MGC116788
  • interleukin 13
  • MGC116786
  • NC30
  • P600

Background

IL-13 (Interleukin-13) plays a key role in the pathogenesis of allergy, cancer, and tissue fibrosis. It is secreted by several helper T cell subsets, NK cells, mast cells, eosinophils, basophils, and visceral smooth muscle cells. IL-13 suppresses the production of proinflammatory cytokines and other cytotoxic substances by macrophages, fibroblasts, and endothelial cells. It promotes B cell activation, immunoglobulin class switching to IgE, and the upregulation of CD23/Fc epsilon RII. IL-13 signals through a receptor complex containing IL-13 R alpha 1 and IL-4 R alpha. This complex also functions as the type 2 IL-4 receptor. IL-13 R alpha 2 binds IL-13 and prevents IL-13 from signaling through the IL-13 R alpha 1/IL-4 R alpha complex. IL-13-bound IL-13 R alpha 2 can directly promote tumor cell invasiveness and the development of tissue fibrosis.
⚠ WARNING: This product can expose you to chemicals including N,N-Dimethylforamide, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov.

Publications for IL-13 (M1300CB)(134)

We have publications tested in 3 confirmed species: Human, Mouse, Transgenic Mouse.

We have publications tested in 1 application: ELISA Capture.


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ELISA Capture
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Human
(2)
Mouse
(132)
Transgenic Mouse
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Showing Publications 1 - 10 of 134. Show All 134 Publications.
Publications using M1300CB Applications Species
Achlaug, L;Awwad, L;Langier Goncalves, I;Goldenberg, T;Aronheim, A; Tumor Growth Ameliorates Cardiac Dysfunction and Suppresses Fibrosis in a Mouse Model for Duchenne Muscular Dystrophy International journal of molecular sciences 2023-08-09 [PMID: 37628775] (Mouse) Mouse
Irie, M;Kabata, H;Sasahara, K;Kurihara, M;Shirasaki, Y;Kamatani, T;Baba, R;Matsusaka, M;Koga, S;Masaki, K;Miyata, J;Araki, Y;Kikawada, T;Kabe, Y;Suematsu, M;Yamagishi, M;Uemura, S;Moro, K;Fukunaga, K; Annexin A1 is a cell-intrinsic metalloregulator of zinc in human ILC2s Cell reports 2023-06-07 [PMID: 37294636] (Transgenic Mouse, Mouse) Transgenic Mouse, Mouse
Y Nishimoto, D Ando, K Irie, I Kainuma, Y Katayama, S Sato, T Suzuki, M Harada, T Yoshida, K Ito, Y Kizawa Dasatinib attenuates airway inflammation of asthma exacerbation in mice induced by house dust mites and dsRNA Biochemistry and Biophysics Reports, 2022-12-02;33(0):101402. 2022-12-02 [PMID: 36478895] (Mouse) Mouse
GJ Wang, X Dong, Y Li Cluster of Differentiation 147 (CD147) serves as a promoter of atherosclerosis in patients with cerebral infarction European review for medical and pharmacological sciences, 2022-08-01;26(16):5710-5717. 2022-08-01 [PMID: 36066144] (Human) Human
JO Lim, YH Kim, IS Lee, WI Kim, SJ Lee, SW Pak, IS Shin, T Kim Cinnamomum cassia (L.) J.Presl Alleviates Allergic Responses in Asthmatic Mice via Suppression of MAPKs and MMP-9 Frontiers in Pharmacology, 2022-08-11;13(0):906916. 2022-08-11 [PMID: 36034804] (Mouse) Mouse
A Kanamori, F Tanaka, M Ominami, Y Nadatani, S Fukunaga, K Otani, S Hosomi, N Kamata, Y Nagami, K Taira, Y Fujiwara Psychological Stress Exacerbates Inflammation of the Ileum via the Corticotropin-Releasing Hormone-Mast Cell Axis in a Mouse Model of Eosinophilic Enteritis International Journal of Molecular Sciences, 2022-08-01;23(15):. 2022-08-01 [PMID: 35955675] (Mouse) Mouse
BW Lewis, ML Ford, AQ Khan, J Walum, RD Britt Chronic Allergen Challenge Induces Corticosteroid Insensitivity With Persistent Airway Remodeling and Type 2 Inflammation Frontiers in Pharmacology, 2022-04-11;13(0):855247. 2022-04-11 [PMID: 35479312] (Mouse) Mouse
B Kassa, MH Lee, R Kumar, C Mickael, L Sanders, RM Tuder, M Mentink-Ka, BB Graham Experimental Schistosoma japonicum-induced pulmonary hypertension PloS Neglected Tropical Diseases, 2022-04-13;16(4):e0010343. 2022-04-13 [PMID: 35417453] (Mouse) Mouse
DH Lee, HK Park, HR Lee, H Sohn, S Sim, HJ Park, YS Shin, YK Kim, Y Choi, HS Park Immunoregulatory effects of Lactococcus lactis-derived extracellular vesicles in allergic asthma Clinical and translational allergy, 2022-03-01;12(3):e12138. 2022-03-01 [PMID: 35344296] (Mouse) Mouse
K Shinoda, A Choe, K Hirahara, M Kiuchi, K Kokubo, T Ichikawa, JS Hoki, AS Suzuki, N Bose, JA Appleton, RV Aroian, FC Schroeder, PW Sternberg, T Nakayama Nematode ascarosides attenuate mammalian type 2 inflammatory responses Proceedings of the National Academy of Sciences of the United States of America, 2022-03-01;119(9):. 2022-03-01 [PMID: 35210367] (Mouse) Mouse
Show All 134 Publications.

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Bioinformatics

Gene Symbol Il13