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Kv7.2 Antibody

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Western Blot: Kv7.2 Antibody [NBP2-85190] - WB Suggested Anti-KCNQ2 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:12500. Positive Control: HepG2 cell lysate

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
0.5 mg/ml

Order Details

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Kv7.2 Antibody Summary

Immunogen
The immunogen is a synthetic peptide directed towards the N-terminal region of human Kv7.2. Peptide sequence: YRGWRGRLKFARKPFCVIDIMVLIASIAVLAAGSQGNVFATSALRSLRFL The peptide sequence for this immunogen was taken from within the described region.
Clonality
Polyclonal
Host
Rabbit
Gene
KCNQ2
Purity
Affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 1.0 ug/ml

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS, 2% Sucrose
Preservative
0.09% Sodium Azide
Concentration
0.5 mg/ml
Purity
Affinity purified

Alternate Names for Kv7.2 Antibody

  • BFNC
  • BFNS1
  • EBN
  • EBN1
  • EIEE7
  • ENB1
  • HNSPC
  • KCNA11
  • KCNQ2
  • KQT-like 2
  • Kv7.2
  • KVEBN1
  • neuroblastoma-specific potassium channel protein
  • Neuroblastoma-specific potassium channel subunit alpha KvLQT2
  • potassium voltage-gated channel subfamily KQT member 2
  • potassium voltage-gated channel, KQT-like subfamily, member 2
  • Voltage-gated potassium channel subunit Kv7.2

Background

KCNQs are members of the voltage dependent non inactivating potassium channel family. Currently there are five known KCNQs (KCNQ1 to 5) found in the central nervous system and KCNQ2 and 3 have demonstrated their importance in M current activation. Studies have shown that KCNQ2 and KCNQ3 form heteromultimers that, when formed, substantially increase the M current. Inhibition of M current controls neuron excitability throughout the nervous system as well as the responsiveness to synaptic inputs. Genetic mutations in these proteins have been linked to disorders such as benign familial neonatal convulsions (BFNC), deafness, neuropathic pain and epilepsy.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol KCNQ2