Recombinant Human KAT2A/GCN5 His Protein

GCN5L2(General control of amino acid synthesis protein 5 like 2) belongs to the GCN5 family. It functions as a histone acetyltransferase (HAT) to promote transcriptional activation. Acetylation of histones gives a specific tag for epigenetic transcription activation. GCN5L2 has been shown to interact with Ku70, TAF9, transcription initiation protein SPT3 homolog, TADA2L, Ku80 and DDB1. Recombinant human GCN5L2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: In vitro.

Showing Publications 1 - 2 of 2.

Publications using NBP1-72426	Applications	Species
Pacifico R Pyridine-Based 1, 2, 3-Triazoles: a new class of potential KAT2A inhibitors and scaffolds for CH activation and catalysis Thesis 2023-01-01
Hu J, Xia X, Zhao Q, Li S Lysine acetylation of NKG2D ligand Rae-1 stabilizes the protein and sensitizes tumor cells to NKG2D immune surveillance Cancer letters 2020-12-03 [PMID: 33279621] (In vitro, Human) Details: HEK293 cells transfected with Rae-1 plasmids	In vitro	Human

Array NBP1-72426

• KAT2A/GCN5 Antibodies
• KAT2A/GCN5 Protein