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Integrin beta 7 Antibody (2G18) - Azide and BSA Free

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Immunohistochemistry: Integrin beta 7 Antibody (2G18) [NB110-94147] - LPAM-1 immunohistochemistry staining of paraffin sections of mouse spleen from LPS exposed animals.

Product Details

Summary
Reactivity MuSpecies Glossary
Applications Flow, IHC, IP
Clone
2G18
Clonality
Monoclonal
Host
Rat
Conjugate
Unconjugated
Format
Azide and BSA Free
Concentration
LYOPH

Order Details

Integrin beta 7 Antibody (2G18) - Azide and BSA Free Summary

Immunogen
Cell lysates of mouse lymphocytes
Isotype
IgG2
Clonality
Monoclonal
Host
Rat
Gene
ITGB7
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry 1:50-1:200
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:100-200
  • Immunoprecipitation 1:100-1:400

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
Lyophilized from a 0.2 um filtered solution in PBS. 0.025 mg size is provided in liquid form, PBS
Preservative
No Preservative
Concentration
LYOPH
Purity
Protein A or G purified
Reconstitution Instructions
Reconstitute the antibody with 250 ul sterile PBS (final concentration 400ug/ml).

Alternate Names for Integrin beta 7 Antibody (2G18) - Azide and BSA Free

  • Gut homing receptor beta subunit
  • integrin beta 7 subunit
  • Integrin beta 7
  • integrin beta-7
  • integrin, beta 7
  • ITGB7

Background

Integrin alpha 4 beta 7, also known as, the lymphocyte Peyer's patch adhesion molecule (LPAM1) is a member of the integrin family of cell surface receptors. It is expressed primarily on mucosal lymphocytes, but is also present on NK cells and eosinophils. The alpha 4 beta 7 heterodimer mediates the binding of lymphocytes to its ligand, mucosal vascular addressin (MAdCAM1) on the high endothelial venules, thereby directing the homing of lymphocytes into Peyer's patches and intestinal lamina propria. This antibody has been shown to be useful for studies of the induction of homotypic cellular aggregation and the blockade of binding to cell adhesion molecules.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol ITGB7
Entrez