| Reactivity | HuSpecies Glossary |
| Applications | Flow, ICC/IF, ICC/IF |
| Clone | DF1524 |
| Clonality | Monoclonal |
| Host | Mouse |
| Conjugate | FITC |
| Immunogen | Human Integrin alpha L/CD11a protein (Uniprot: P20701) |
| Localization | Cell Surface |
| Specificity | Recognizes a protein of 180kDa, identified as CD11a (Leucocyte Workshop IV; Code 1524). CD11a complex with the 2 subunit of the integrin family, CD18, to form the cell surface heterodimer, LFA-1 or CD11a /C18 (aLbL). LFA-1 is expressed on all leukocytes including lymphocytes, monocytes, and granulocytes. It is involved in leukocyte adhesion to its ligands including intercellular adhesion molecule-1 (ICAM-1 or CD54), ICAM-2 (CD102), ICAM-3 (CD50) and Telencephalin (TLN) and play a role in most immune/inflammatory responses. This monoclonal antibody potently blocks LFA-1 dependent homotypic cell aggregation. |
| Isotype | IgG2b Kappa |
| Clonality | Monoclonal |
| Host | Mouse |
| Gene | ITGAL |
| Purity | Protein A or G purified |
| Innovator's Reward | Test in a species/application not listed above to receive a full credit towards a future purchase. |
| Dilutions |
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| Application Notes | Optimal dilution of this antibody should be experimentally determined. |
| Storage | Store at 4C in the dark. |
| Buffer | PBS |
| Preservative | 0.05% Sodium Azide |
| Purity | Protein A or G purified |
Secondary Antibodies |
Isotype Controls |
Research Areas for Integrin alpha L/CD11a Antibody (NBP3-11533F)Find related products by research area.
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| Gene Symbol | ITGAL |
