| Reactivity | MuSpecies Glossary |
| Applications | WB, CyTOF-ready, Flow |
| Clone | 234205 |
| Clonality | Monoclonal |
| Host | Rat |
| Conjugate | Unconjugated |
| Immunogen | Chinese hamster ovary cell line CHO-derived recombinant mouse IL‑27 Tyr19-Pro228 (EBI3) & Phe29-Ser234 (p28) Accession # O35228 (EBI3) & Q8K3I6 (p28) |
| Specificity | Detects mouse IL-27 in Western blots. This antibody recognizes the p28 subunit either as part of a p28/EBI-3 heterodimer or as a free subunit. |
| Source | N/A |
| Isotype | IgG2b |
| Clonality | Monoclonal |
| Host | Rat |
| Gene | Il27 |
| Purity Statement | Protein A or G purified from hybridoma culture supernatant |
| Innovator's Reward | Test in a species/application not listed above to receive a full credit towards a future purchase. |
| Dilutions |
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| Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
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| Buffer | Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS. |
| Preservative | No Preservative |
| Reconstitution Instructions | Reconstitute at 0.5 mg/mL in sterile PBS. |
Interleukin 27 (IL-27) is a novel heterodimeric cytokine comprised of the IL-12 p35-related protein, p28, and the IL-12 p40-related protein, EBI-3 (Epstein‑Barr virus‑induced gene 3). IL-27 binds TCCR/WSX-1 on naïve CD4+ T cells and induces the expression of a functional IL-12 receptor, making these cells sensitive to IL‑12‑mediated Th1 cell development.
Secondary Antibodies |
Isotype Controls |
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| Gene Symbol | Il27 |
| Uniprot |
