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HSPB8/HSP22 Antibody (OTI1E3) [DyLight 350]

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Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications Flow, ICC/IF
Clone
OTI1E3
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 350

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-71828AF350
Alexa Fluor 405
NBP2-71828AF405
Alexa Fluor 488
NBP2-71828AF488
Alexa Fluor 532
NBP2-71828AF532
Alexa Fluor 594
NBP2-71828AF594
Alexa Fluor 647
NBP2-71828AF647
Alexa Fluor 700
NBP2-71828AF700
Alexa Fluor 750
NBP2-71828AF750
Allophycocyanin
NBP2-71828APC
Biotin
NBP2-71828B
DyLight 405
NBP2-71828V
DyLight 488
NBP2-71828G
DyLight 550
NBP2-71828R
DyLight 594
NBP2-71828DL594
DyLight 650
NBP2-71828C
DyLight 680
NBP2-71828FR
DyLight 755
NBP2-71828IR
FITC
NBP2-71828F
HRP
NBP2-71828H
Janelia Fluor 549
NBP2-71828JF549
Janelia Fluor 646
NBP2-71828JF646
PE
NBP2-71828PE
PerCP
NBP2-71828PCP
Unconjugated
NBP2-02576
mFluor Violet 450 SE
NBP2-71828MFV450
mFluor Violet 500 SE
NBP2-71828MFV500
mFluor Violet 610 SE
NBP2-71828MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP2-02576
Azide and BSA Free
NBP2-71828
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HSPB8/HSP22 Antibody (OTI1E3) [DyLight 350] Summary

Immunogen
Full length recombinant protein of human HSPB8/HSP22 (NP_055180) produced in HEK293T cells.
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
HSPB8
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Flow Cytometry
  • Immunocytochemistry/ Immunofluorescence
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Mouse-On-Mouse blocking reagent may be needed for IHC and ICC experiments to reduce high background signal. You can find these reagents under catalog numbers PK-2200-NB and MP-2400-NB. Please contact Technical Support if you have any questions.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for HSPB8/HSP22 Antibody (OTI1E3) [DyLight 350]

  • Alpha-crystallin C chain
  • CMT2L
  • CRYAC
  • DHMN2
  • E2IG1
  • E2IG1E2-induced gene 1 protein
  • H11
  • H11DHMN2
  • heat shock 22kDa protein 8
  • heat shock 27kDa protein 8
  • heat shock protein beta-8
  • HMN2
  • HMN2A
  • HSP22
  • HSP22CMT2L
  • HSPB8
  • Protein kinase H11
  • Small stress protein-like protein HSP22

Background

HSP22 is encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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HSPB8/HSP22 Antibody (OTI1E3) [DyLight 350]
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Product General Protocols

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Video Protocols

ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol HSPB8