GAB2 Antibody

This gene is a member of the GRB2-associated binding protein (GAB) gene family and is similar to the GAB1 gene. These proteins contain pleckstrin homology (PH) domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. They act as adapters for transmitting various signals in response to stimuli through cytokine and growth factor receptors, and T- and B-cell antigen receptors. The protein encoded by this gene is the principal activator of phosphatidylinositol-3 kinase in response to activation of the high affinity IgE receptor. Two alternatively spliced transcripts encoding different isoforms have been described for this gene.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publication using NB100-61653	Applications	Species
Bentires-Alj M, Gil SG, Chan R et al. A role for the scaffolding adapter GAB2 in breast cance Nat Med 2006-01-01 [PMID: 16369543]

Array NB100-61653

• GAB2 Antibodies
• GAB2 Lysates
• GAB2 Protein