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FoxP1 Antibody (837016) [Allophycocyanin]

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MCF-7 human breast cancer cell line was stained with Mouse Anti-Human FoxP1 APC-conjugated Monoclonal Antibody (Catalog # IC45341A, filled histogram) or isotype control antibody (Catalog # IC002A, open histogram). To facilitate intracellular staining, cells were fixed with 4% paraformaldehyde and permeabilized with methanol. View our protocol for Staining Intracellular Molecules.
MCF-7 human breast cancer cell line was stained with Mouse Anti-Human FoxP1 APC-conjugated Monoclonal Antibody (Catalog # IC45341A, filled histogram) or isotype control antibody (Catalog # IC002A, open histogram). To ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow
Clone
837016
Clonality
Monoclonal
Host
Mouse
Conjugate
Allophycocyanin

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
IC45341U-100UG
Alexa Fluor 405
IC45341V-100UG
Alexa Fluor 488
IC45341G
Alexa Fluor 532
FAB45341X
Alexa Fluor 594
IC45341T-100UG
Alexa Fluor 647
IC45341R-100UG
Alexa Fluor 700
IC45341N-100UG
Alexa Fluor 750
IC45341S-100UG
Biotin
FAB45341B
CoraFluor 1
FAB45341CL1
DyLight 350
FAB45341D
DyLight 405
FAB45341E
DyLight 488
FAB45341K
DyLight 550
FAB45341L
DyLight 594
FAB45341M
DyLight 650
FAB45341W
DyLight 680
FAB45341Y
DyLight 755
FAB45341Z
FITC
FAB45341F
HRP
FAB45341H
Janelia Fluor 525
FAB45341JF525
Janelia Fluor 549
FAB45341I
Janelia Fluor 585
FAB45341JF585
Janelia Fluor 635
FAB45341JF635
Janelia Fluor 646
FAB45341J
Janelia Fluor 669
FAB45341JF669
PE
FAB45341P
PerCP
FAB45341C
Unconjugated
MAB45341
mFluor Violet 450 SE
FAB45341MFV450
mFluor Violet 500 SE
FAB45341MFV500
mFluor Violet 610 SE
FAB45341MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB45341
Carrier Free
MAB45341
Carrier Free
IC45341G
Carrier Free
MAB45341-SP
Carrier Free
IC45341R-100UG
Carrier Free
IC45341N-100UG
Carrier Free
IC45341V-100UG
Carrier Free
IC45341U-100UG
Carrier Free
IC45341T-100UG
Carrier Free
IC45341S-100UG
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FoxP1 Antibody (837016) [Allophycocyanin] Summary

Immunogen
E. coli-derived recombinant human FoxP1
Lys548-Glu677
Accession # Q9H334
Specificity
Detects human FoxP1 in direct ELISAs and Western blots.
Source
N/A
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
FOXP1
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • Intracellular Staining by Flow Cytometry 10 uL/10^6 cells

Packaging, Storage & Formulations

Storage
Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.
Buffer
Supplied in a saline solution containing BSA and Sodium Azide.
Preservative
Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for FoxP1 Antibody (837016) [Allophycocyanin]

  • FLJ23741
  • fork head-related protein like B
  • forkhead box P1
  • forkhead box protein P1
  • FoxP1
  • glutamine-rich factor 1
  • hFKH1B
  • HSPC215
  • MGC12942
  • MGC88572
  • MGC99551
  • QRF1
  • QRF112CC4

Background

Forkhead Box P1 (FOXP1) is a member of the FOX family of transcription factors. FoxP1 has been implicated in cardiac, lung, and lymphocyte development. FoxP1 knock out mice die at embryonic day 14.5 due to heart valve and outflow tract abnormalities. FoxP1 contains both a DNA binding domain as well as protein-protein interaction domains. FoxP1 can homo or heterodimerize with FoxP2 and FoxP4, with dimerization necessary for DNA binding. FoxP1 shows both oncogenic and tumor suppressive characteristics. Overexpression in lymphomas leads to poor prognosis, but loss of FoxP1 in breast cancer also implicates a poor prognosis. Human isoforms of 489 to 677 amino acids contain alternate sequences within the first 60 amino acids and/or deletion of amino acids.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol FOXP1
Uniprot