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CD45RA Antibody (OTH-74D4) [mFluor Violet 500 SE]

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CD45RA Antibody (OTH-74D4) [mFluor Violet 500 SE] - Vial of mFluor Violet 500 conjugated antibody. mFluor Violet 500 is optimally excited at 410 nm by the Violet laser (405 nm) and has an emission maximum of 501 nm.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, ICC/IF
Clone
OTH-74D4
Clonality
Monoclonal
Host
Rabbit
Conjugate
mFluor Violet 500 SE

Order Details

CD45RA Antibody (OTH-74D4) [mFluor Violet 500 SE] Summary

Additional Information
Recombinant Monoclonal Antibody
Immunogen
This antibody was raised by immunising mice with an EBV-transformed B cell line from a patient with MHC class II deficiency.
Specificity
OTH-74D4 antibody recognises CD45RA, which is an CD45 isoform containing only protein A region.The CD45RA antigen is expressed mostly on naive CD4+, CD8+ and gd+ T and on most B and NK lymphocytes. Generally the CD45RA antigen density decreases upon activation.
Isotype
IgG Kappa
Clonality
Monoclonal
Host
Rabbit
Gene
PTPRC
Purity
Protein A purified
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Applications/Dilutions

Dilutions
  • Flow Cytometry
  • Immunofluorescence
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A purified

Alternate Names for CD45RA Antibody (OTH-74D4) [mFluor Violet 500 SE]

  • B220
  • CD45 antigen
  • CD45R
  • CD45RA
  • EC 3.1.3.48
  • L-CA
  • LY5
  • protein tyrosine phosphatase, receptor type, C
  • receptor-type tyrosine-protein phosphatase C
  • T200 glycoprotein
  • T200 leukocyte common antigen
  • T200receptor type, c polypeptide

Background

The CD45 molecule is comprised of different glycoproteins ranging from 180-240 kD. Expression of CD45 is found on all hemopoietic cells. Detection of the different isoforms can distinguish between different cell forms i.e. naive T cells and memory T cells. CD45RA is an isoform of the CD45 complex and has restricted expression between different subtypes of lymphoid cells. The functional activity of each CD45 isotype also varies.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Calculators

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Bioinformatics

Gene Symbol PTPRC