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CD41/CD61 Antibody (PAC-1) [DyLight 680]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, IP, ICC/IF
Clone
PAC-1
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 680

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-62201AF350
Alexa Fluor 405
NBP2-62201AF405
Alexa Fluor 488
NBP2-62201AF488
Alexa Fluor 532
NBP2-62201AF532
Alexa Fluor 594
NBP2-62201AF594
Alexa Fluor 647
NBP2-62201AF647
Alexa Fluor 700
NBP2-62201AF700
Alexa Fluor 750
NBP2-62201AF750
Allophycocyanin
NBP2-62201APC
Biotin
NBP2-62201B
DyLight 350
NBP2-62201UV
DyLight 405
NBP2-62201V
DyLight 488
NBP2-62201G
DyLight 550
NBP2-62201R
DyLight 594
NBP2-62201DL594
DyLight 650
NBP2-62201C
DyLight 755
NBP2-62201IR
FITC
NBP2-62201F
HRP
NBP2-62201H
Janelia Fluor 549
NBP2-62201JF549
Janelia Fluor 646
NBP2-62201JF646
PE
NBP2-62201PE
PerCP
NBP2-62201PCP
Unconjugated
NBP2-62201
mFluor Violet 450 SE
NBP2-62201MFV450
mFluor Violet 500 SE
NBP2-62201MFV500
mFluor Violet 610 SE
NBP2-62201MFV610
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CD41/CD61 Antibody (PAC-1) [DyLight 680] Summary

Immunogen
Human platelets
Specificity
The mouse monoclonal antibody PAC-1 recognizes an extracellular activation-induced conformational epitope PAC-1 on CD41/CD61 complex (gpIIb/IIIa), also known as integrin alpha IIb beta 3, a receptor which mediates platelet aggregation.
Isotype
IgM Kappa
Clonality
Monoclonal
Host
Mouse
Gene
ITGA2B
Purity
Chromatography
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Applications/Dilutions

Dilutions
  • Flow (Cell Surface)
  • Flow Cytometry
  • Immunocytochemistry
  • Immunoprecipitation
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Chromatography

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for CD41/CD61 Antibody (PAC-1) [DyLight 680]

  • CD41 antigen
  • CD41
  • CD41BHPA3
  • GP2Bintegrin alpha-IIb
  • GPalpha IIb
  • GPIIb
  • GTA
  • integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigenCD41)
  • integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigenCD41B)
  • ITGAB
  • platelet fibrinogen receptor, alpha subunit
  • Platelet membrane glycoprotein IIb
  • platelet-specific antigen BAK

Background

Integrin alpha 2b (CD41) is a calcium-dependent, noncovalently associated heterodimer and contains a heavy chain (GPIIb alpha) and a light chain (GPIIb beta) linked by a single disulfide bond. The Integrin alpha 2B chain interacts with the Integrin beta 3 subunit/CD61 to form the platelet glycoprotein complex, gpIIb/IIIa. It is expressed on platelets and megakaryocytes. Ligands for the gpIIb/IIIa heterodimer include fibrinogen, von Willebrand factor, fibronectin, vitronectin, and thrombospondin. The gpIIb/IIIa complex is the major Integrin on platelets and is important for platelet adhesion and aggregation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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FAQs for CD41/CD61 Antibody (NBP2-62201FR) (0)

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Secondary Antibodies

 

Isotype Controls

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Product PDFs

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Calculators

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Bioinformatics

Gene Symbol ITGA2B