Note: Mouseover a species abbreviation on the product page to display the fullname.
How can we help you?
![Western Blot: PrPC Antibody [NB100-56605] - Analysis of BSE in (A) recombinant fusion protein containing amino acids 162-170 and (B) fusion partner without these amino acids, using this antibody at 5 ug/ml.](http://images.novusbio.com/fullsize/Prion-protein-Antibody-Western-Blot-NB100-56605-img0002.jpg "Western Blot: PrPC Antibody [NB100-56605] - Analysis of BSE in (A) recombinant fusion protein containing amino acids 162-170 and (B) fusion partner without these amino acids, using this antibody at 5 ug/ml.")
![Western Blot: PrPC Antibody [NB100-56604] - Analysis of BSE in (A) recombinant fusion protein containing amino acids 142-148 and (B) fusion partner without these amino acids, using this antibody. 5 ug/ml.](http://images.novusbio.com/fullsize/Prion-protein-Antibody-Western-Blot-NB100-56604-img0002.jpg "Western Blot: PrPC Antibody [NB100-56604] - Analysis of BSE in (A) recombinant fusion protein containing amino acids 142-148 and (B) fusion partner without these amino acids, using this antibody. 5 ug/ml.")
![Western Blot: PrPC Antibody [NB100-56606] - Analysis of BSE in (A) recombinant fusion protein containing amino acids 217-229 and (B) fusion partner without these amino acids, using this antibody. 5 ug/ml.](http://images.novusbio.com/fullsize/Prion-protein-Antibody-Western-Blot-NB100-56606-img0002.jpg "Western Blot: PrPC Antibody [NB100-56606] - Analysis of BSE in (A) recombinant fusion protein containing amino acids 217-229 and (B) fusion partner without these amino acids, using this antibody. 5 ug/ml.")
![Immunocytochemistry/Immunofluorescence: PrPC Antibody [NBP2-38508] - Staining of human cell line U-2 OS shows localization to nuclear membrane & cytosol. Antibody staining is shown in green.](http://images.novusbio.com/fullsize/Prion-protein-Antibody-Immunocytochemistry-Immunofluorescence-NBP2-38508-img0003.jpg "Immunocytochemistry/Immunofluorescence: PrPC Antibody [NBP2-38508] - Staining of human cell line U-2 OS shows localization to nuclear membrane & cytosol. Antibody staining is shown in green.")
![Immunohistochemistry-Paraffin: PrPC Antibody [NBP2-38508] - Staining of human pancreas shows no positivity in exocrine glandular cells as expected.](http://images.novusbio.com/fullsize/PrPC-Antibody-Immunohistochemistry-Paraffin-NBP2-38508-img0007.jpg)
![Immunohistochemistry-Paraffin: PrPC Antibody [NBP2-38508] - Staining of human cerebellum shows moderate cytoplasmic positivity in Purkinje cells.](http://images.novusbio.com/fullsize/Prion-protein-Antibody-Immunohistochemistry-NBP2-38508-img0002.jpg)
![Immunohistochemistry-Paraffin: PrPC Antibody [NBP2-38508] - Staining of human cerebral cortex shows strong granuclar cytoplasmic positivity in neurons.](http://images.novusbio.com/fullsize/PrPC-Antibody-Immunohistochemistry-Paraffin-NBP2-38508-img0005.jpg)
![Immunohistochemistry-Paraffin: PrPC Antibody [NBP2-38508] - Staining of human skeletal muscle shows no positivity in myocytes as expected.](http://images.novusbio.com/fullsize/PrPC-Antibody-Immunohistochemistry-Paraffin-NBP2-38508-img0006.jpg)
![Western Blot: PrPC Antibody (S03-2E2) [NBP3-19967] - Western blot detection of PrPC in Rat Brain and Mouse Brain lysates using NBP3-19967 (1:1000 diluted). Predicted band size: 28kDa. Observed band size: 28kDa.](http://images.novusbio.com/fullsize/PrPC-Antibody-S03-2E2-Western-Blot-NBP3-19967-img0002.jpg "Western Blot: PrPC Antibody (S03-2E2) [NBP3-19967] - Western blot detection of PrPC in Rat Brain and Mouse Brain lysates using NBP3-19967 (1:1000 diluted). Predicted band size: 28kDa. Observed band size: 28kDa.")
![Immunohistochemistry-Paraffin: PrPC Antibody (S03-2E2) [NBP3-19967] - Immunohistochemistry of Prion protein in paraffin-embedded Human breast cancer tissue using NBP3-19967 at dilution 1/20](http://images.novusbio.com/fullsize/PrPC-Antibody-S03-2E2-Immunohistochemistry-Paraffin-NBP3-19967-img0001.jpg)
![Western Blot: PrPC Antibody (T16-R) [NBP1-71667] - PrPC protein in mouse brain extract (A), HEK293 cells producing recombinant human prion protein (B), and cells transfected with empty vector (C). 200 ug of total protein loaded per well.](http://images.novusbio.com/fullsize/Prion-protein-Antibody-T16-R-Western-Blot-NBP1-71667-img0008.jpg "Western Blot: PrPC Antibody (T16-R) [NBP1-71667] - PrPC protein in mouse brain extract (A), HEK293 cells producing recombinant human prion protein (B), and cells transfected with empty vector (C). 200 ug of total protein loaded per well.")
![Western Blot: PrPC Antibody (3F4) [NBP3-23335] - Western blot of GST recombinant human full-length prion protein that was untreated (lanes 1 and 3) or phosphorylated with Cdk5/p25 (lanes 2 & 4). Endogenous prion phosphorylation was examined in human PC3 cells untreated (lanes 5 & 7) or treated with Calyculin A (100 nM) for 30 min (lanes 6 & 8). The blots were probed with anti-Prion protein (3F4) (lanes 1, 2, 5, & 6) or anti-Prion protein (Ser-43) (lanes 3, 4, 7, & 8).](http://images.novusbio.com/fullsize/nbp3-23335_mouse-prpc-mab-3f4-19920231911475.jpg "Western Blot: PrPC Antibody (3F4) [NBP3-23335] - Western blot of GST recombinant human full-length prion protein that was untreated (lanes 1 and 3) or phosphorylated with Cdk5/p25 (lanes 2 & 4). Endogenous prion phosphorylation was examined in human PC3 cells untreated (lanes 5 & 7) or treated with Calyculin A (100 nM) for 30 min (lanes 6 & 8). The blots were probed with anti-Prion protein (3F4) (lanes 1, 2, 5, & 6) or anti-Prion protein (Ser-43) (lanes 3, 4, 7, & 8).")
![Western Blot: PrPC [p Ser43] Antibody [NBP3-23337] - Western blot of GST recombinant human full-length prion protein that was untreated (lanes 1 and 3) or phosphorylated with Cdk5/p25 (lanes 2 & 4). Endogenous prion phosphorylation was examined in human PC3 cells untreated (lanes 5 & 7) or treated with Calyculin A (100 nM) for 30 min (lanes 6 & 8). The blots were probed with anti-Prion protein (3F4) (lanes 1, 2, 5, & 6) or anti-Prion protein (Ser-43) (lanes 3, 4, 7, & 8).](http://images.novusbio.com/fullsize/nbp3-23337_rabbit-prpc-p-ser43-pab-19920231410133.jpg "Western Blot: PrPC [p Ser43] Antibody [NBP3-23337] - Western blot of GST recombinant human full-length prion protein that was untreated (lanes 1 and 3) or phosphorylated with Cdk5/p25 (lanes 2 & 4). Endogenous prion phosphorylation was examined in human PC3 cells untreated (lanes 5 & 7) or treated with Calyculin A (100 nM) for 30 min (lanes 6 & 8). The blots were probed with anti-Prion protein (3F4) (lanes 1, 2, 5, & 6) or anti-Prion protein (Ser-43) (lanes 3, 4, 7, & 8).")
![Western Blot: PrPC Antibody (3D0J9) [NBP3-16708] - Western blot analysis of extracts of various cell lines, using PrPC Rabbit mAb (NBP3-16708) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.](http://images.novusbio.com/fullsize/PrPC-Antibody-3D0J9-Western-Blot-NBP3-16708-img0001.jpg "Western Blot: PrPC Antibody (3D0J9) [NBP3-16708] - Western blot analysis of extracts of various cell lines, using PrPC Rabbit mAb (NBP3-16708) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.")
![Knockout Validated: PrPC Antibody [NBP3-03595] - Analysis of extracts from normal (control) and PRNP knockout (KO) HeLa cells, using PrPC (PRNP) protein antibody at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST.](http://images.novusbio.com/fullsize/PrPC-Antibody-Knockout-Validated-NBP3-03595-img0001.jpg "<b>Genetic Strategies Validation. </b>Knockout Validated: PrPC Antibody [NBP3-03595] - Analysis of extracts from normal (control) and PRNP knockout (KO) HeLa cells, using PrPC (PRNP) protein antibody at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST.")
![Immunohistochemistry-Paraffin: PrPC Antibody [NBP1-92285] - Staining of human skeletal muscle shows no positivity in myocytes as expected.](http://images.novusbio.com/fullsize/Prion-protein-Antibody-Immunohistochemistry-Paraffin-NBP1-92285-img0005.jpg "Immunohistochemistry-Paraffin: PrPC Antibody [NBP1-92285] - Staining of human skeletal muscle shows no positivity in myocytes as expected.")
![<b>Orthogonal Strategies Validation. </b>Immunohistochemistry-Paraffin: PrPC Antibody [NBP1-92285] - Analysis in human cerebral cortex and skeletal muscle tissues. Corresponding PrPC (PRNP) RNA-seq data are presented for the same tissues.](http://images.novusbio.com/fullsize/Prion-protein-Antibody-Immunohistochemistry-Paraffin-NBP1-92285-img0001.jpg)
![Immunohistochemistry-Paraffin: PrPC Antibody [NBP1-92285] - Staining of human cerebral cortex shows weak to moderate cytoplasmic positivity in neurons.](http://images.novusbio.com/fullsize/Prion-protein-Antibody-Immunohistochemistry-Paraffin-NBP1-92285-img0002.jpg)
![Immunohistochemistry-Paraffin: PrPC Antibody [NBP1-92285] - Staining of human skin shows weak to moderate cytoplasmic positivity in keratinocytes.](http://images.novusbio.com/fullsize/Prion-protein-Antibody-Immunohistochemistry-Paraffin-NBP1-92285-img0003.jpg)
![Immunohistochemistry-Paraffin: PrPC Antibody [NBP1-92285] - Staining of human liver shows weak to moderate cytoplasmic positivity in hepatocytes](http://images.novusbio.com/fullsize/Prion-protein-Antibody-Immunohistochemistry-Paraffin-NBP1-92285-img0004.jpg)