Proprotein Convertase 9/PCSK9 Products

Description

PCSK9 encodes a proprotein convertase belonging to the proteinase K subfamily of the secretory subtilase family. The encoded protein is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in the endoplasmic reticulum. The protein may function as a proprotein convertase. This protein plays a role in cholesterol homeostasis and may have a role in the differentiation of cortical neurons. Mutations in this gene have been associated with a third form of autosomal dominant familial hypercholesterolemia (HCHOLA3).

Bioinformatics

Uniprot	NM_174936 Human NP_777596.2 Human Q8NBP7 Human
Product By Gene ID	255738
Alternate Names	EC 3.4.21 EC 3.4.21.111 FH3neural apoptosis regulated convertase 1 HCHOLA3 hypercholesterolemia, autosomal dominant 3 LDLCQ1 NARC-1convertase subtilisin/kexin type 9 preproprotein NARC1EC 3.4.21.- Neural apoptosis-regulated convertase 1 PC9 Proprotein convertase 9 proprotein convertase subtilisin/kexin type 9 Subtilisin/kexin-like protease PC9

Research Areas for Proprotein Convertase 9/PCSK9

Find related products by research area and learn more about each of the different research areas below.

Cholesterol Metabolism
Lipid and Metabolism