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NEDD8 Products

Antibodies
NEDD8 Antibody (5B8) - BSA Fr ...
NEDD8 Antibody (5B8) - BSA Free
NBP2-37523
Species: Hu
Applications: WB, ELISA, Flow, ICC/IF, IHC, CyTOF-ready
Host: Mouse Monoclonal
Formulation Catalog # Availability Price  
NEDD8 Antibody [Unconjugated] ...
NEDD8 Antibody [Unconjugated]
AF4936
Species: Hu, Mu, Rt
Applications: WB, IHC
Host: Sheep Polyclonal
Formulation Catalog # Availability Price  
NEDD8 Antibody (1A7) - BSA Fr ...
NEDD8 Antibody (1A7) - BSA Free
NBP2-37524
Species: Hu
Applications: WB, ELISA, Flow, ICC/IF, IHC, CyTOF-ready
Host: Mouse Monoclonal
Formulation Catalog # Availability Price  
Proteins
Recombinant Human/Mouse/Rat N ...
Recombinant Human/Mouse/Rat NEDD8 ...
UL-812
Species: Hu, Mu, Rt
Applications: Enzyme Activity
Formulation Catalog # Availability Price  
NEDD8 Recombinant Protein Ant ...
NEDD8 Recombinant Protein Antigen
NBP2-68600PEP
Species: Hu
Applications: AC
NEDD8 Recombinant Protein Ant ...
NEDD8 Recombinant Protein Antigen
NBP2-68758PEP
Species: Hu
Applications: AC

Description

NEDD8 (Neural precursor cell-Expressed Developmentally Down-regulated genes) is an ubiquitin-like protein which plays an important role in cell cycle control and embryogenesis (1). NEDD8 has been shown to conjugate to nuclear proteins in a manner analogous to ubiquination and sentrinization. The conjugation process is though to be catalyzed by thee enzymes; E1 (NEDD8-activation), E2 (NEDD8-conjugation) and E3 (NEDD8-ligation). NEDD8 is known to conjugate to Cul-4A and other cullins proteins via the carboxy-terminal Gly residue for ubiquitinylation (3) while NUB1 will negatively regulate its expression (4).

Bioinformatics

Uniprot Human
Human
Human
Product By Gene ID 4738
Alternate Names
  • FLJ43224
  • MGC104393
  • MGC125896
  • MGC125897
  • Nedd-8
  • NEDD-8
  • neddylin
  • Neddylin
  • Neural precursor cell expressed developmentally down-regulated protein 8
  • neural precursor cell expressed, developmentally down-regulated 8
  • Ubiquitin-like protein Nedd8

Research Areas for NEDD8

Find related products by research area and learn more about each of the different research areas below.

Cancer

Related NEDD8 Blog Posts

Check out the latest blog posts on NEDD8.
PINK1: All work and no fun
The protein PINK1 is a mitochondrial-located serine/threonine kinase (PTK) that maintains organelle function and integrity. It not only protects organelles from cellular stress, but it also uses the selective auto-phagocytosis process for cleaning and...    Read more.
Read more NEDD8 related blogs.