MDC1 Products

Description

MDC1 works with H2AX to promote recruitment of repair proteins to the sites of DNA breaks and controls damage-induced cell-cycle arrest checkpoints. Cells that lack MDC1 are sensitive to ionizing radiation.

Bioinformatics

Entrez	9656 Human
Uniprot	Q14676 Human
Product By Gene ID	9656
Alternate Names	DKFZp781A0122 Em:AB023051.5 KIAA0170MGC166888 mediator of DNA damage checkpoint 1 mediator of DNA damage checkpoint protein 1 mediator of DNA-damage checkpoint 1 NFBD1homologue to Drosophila photoreceptor protein calphotin Nuclear factor with BRCT domains 1

Research Areas for MDC1

Find related products by research area and learn more about each of the different research areas below.

Autophagy
DNA Repair

Related MDC1 Blog Posts

Check out the latest blog posts on MDC1.

Further unraveling the role of gamma H2AX in DNA damage response Our genome experiences a moderate amount of DNA damage in our cells on a daily basis.  This DNA damage can be in response to external environmental factors, or be a result of our internal metabolic processes going awry.  While normal rates of DNA ...    Read more.

Read more MDC1 related blogs.