Species: Hu, Mu
Applications: WB, ICC/IF
Host: Mouse Polyclonal
Species: Hu, Mu, Rt
Applications: ICC/IF
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt
Applications: WB
Host: Mouse monoclonal
Species: Hu
Applications: WB
Species: Hu
Applications: WB, ELISA, MA, AP
Species: Hu
Applications: AC
Description
Transcription factors containing a basic helix-loop-helix (bHLH) motif regulate expression of tissue-specific genes ina number of mammalian and insect systems. DNA-binding activity of the bHLH proteins is dependent on formation of homo-and/or heterodimers. Dominant-negative HLH proteins encoded by Id-related genes, such as ID4, also contain theHLH-dimerization domain but lack the DNA-binding basic domain. Consequently, Id proteins inhibit binding to DNA andtranscriptional transactivation by heterodimerization with bHLH proteins (Pagliuca et al., 1995 (PubMed7665172)).(supplied by OMIM)
Bioinformatics
| Entrez |
Mouse
Rat
Human
|
| Uniprot |
Human
Human
Human
|
| Product By Gene ID |
3400 |
| Alternate Names |
- bHLHb27BHLHB27
- Class B basic helix-loop-helix protein 27
- DNA-binding protein inhibitor ID-4
- IDB4
- Inhibitor of DNA binding 4
- inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
|
