ICEBERG Products

Description

ICEBERG, also known as Caspase recruitment domain-containing protein 18, is a 90 amino acid protein that is 10 kDa, most often expressed in the heart and placenta, down-regulates the release of IL1B, and by interacting with caspase-1 and preventing its association with RIP2 inhibits the generation of IL-1-beta. This protein is being studied for its involvement in chronic lymphocytic leukemia. The ICEBERG protein has been linked to the NOD-like receptor signaling pathway where it interacts with CASP1, CARD8, CARD16, and CARD17.

Bioinformatics

Entrez	59082 Human
Uniprot	NP_067546 Human NP_067546.1 Human P57730 Human
Product By Gene ID	59082
Alternate Names	caspase recruitment domain family, member 18 Caspase-1 inhibitor Iceberg ICEBERG caspase-1 inhibitor ICEBERGcaspase recruitment domain-containing protein 18 pseudo-ICE UNQ5804

Research Areas for ICEBERG

Find related products by research area and learn more about each of the different research areas below.

Apoptosis
Cancer