| Formulation | Catalog # | Availability | Price | |
|---|---|---|---|---|
| Carrier Free | AF560-SP | |||
| Formulation | Catalog # | Availability | Price | |
|---|---|---|---|---|
| Carrier Free | AF714-SP | |||
| Formulation | Catalog # | Availability | Price | |
|---|---|---|---|---|
| Carrier Free | 560-GR-100/CF | |||
| Formulation | Catalog # | Availability | Price | |
|---|---|---|---|---|
| Carrier Free | MAB560-SP | |||
| Formulation | Catalog # | Availability | Price | |
|---|---|---|---|---|
| Carrier Free | MAB7141-SP | |||
| Formulation | Catalog # | Availability | Price | |
|---|---|---|---|---|
| BSA Free | NBP1-77043-0.025mg | |||
![Expression of genes in the RA signaling pathway and the specificity of RAR gamma expression by NGN3+ spermatogonia. (A) Scatter plot comparing the levels of transcripts expressed by GFR alpha 1+ and NGN3+ cells according to microarray analysis. For each fraction, average values from three independent RNA samples sorted from different animals are shown. The middle line indicates a difference of 0, and the outer lines represent ratios {log2([NGN3+]/[GFR alpha 1+])} of 1.0 and −1.0. Red dots indicate genes expressed at significantly different levels (P<0.05, t-test with Benjamini–Hochberg correction). Members of the Rar and Rxr gene families are indicated. A list of the genes in this panel is shown in supplementary material Table S2. (B) qRT-PCR analysis of Rara and Rarg mRNA expression in GFR alpha 1+, NGN3+ and KIT+ spermatogonia. Relative copy numbers are shown in arbitrary units after normalization to the amount of Actb mRNA. The mean±s.e.m. values of three independent cell preparations from different animals are shown. *P=0.043, **P=0.011 and ***P=0.0065 (t-test). (C) Representative IF images of whole-mount seminiferous tubules from Ngn3-EGFP mice stained for EGFP, GFR alpha 1 and RAR gamma . (D,E) Frequency of single- and double-positive spermatogonia for the expression of RAR gamma and NGN3 (recognized as RAR gamma +/KIT− and NGN3-EGFP+/KIT−, respectively) (D) and of RAR gamma and GFR alpha 1 (E). Total counts are shown above each bar. Scale bar: 50 μm. Image collected and cropped by CiteAb from the following open publication (//journals.biologists.com/dev/article/doi/10.1242/dev.118695/258623/Hierarchical-differentiation-competence-in), licensed under a CC-BY license. Not internally tested by R&D Systems.](http://images.novusbio.com/fullsize/af560_rat-gfr-alpha-1-gdnf-r-alpha-1-affinity-purified-pab-8220249505971.jpg)
![Western Blot: GFR alpha-1/GDNF R alpha-1 Antibody [NBP1-77043] - Analysis of GFR alpha 1 in crude membrane fractions of human brain (B), liver (L), kidney (K), and spleen (S), respectively, with GFR alpha 1 antibody at 1 ug/mL](http://images.novusbio.com/fullsize/GFR-alpha-1-GDNF-R-alpha-1-Antibody-Western-Blot-NBP1-77043-img0006.jpg "Western Blot: GFR alpha-1/GDNF R alpha-1 Antibody [NBP1-77043] - Analysis of GFR alpha 1 in crude membrane fractions of human brain (B), liver (L), kidney (K), and spleen (S), respectively, with GFR alpha 1 antibody at 1 ug/mL")
![Immunocytochemistry/ Immunofluorescence: GFR alpha-1/GDNF R alpha-1 Antibody - BSA Free [NBP1-77043] - Immunofluorescence of GFR alpha 1 in human brain tissue with GFR alpha 1 antibody at 20 u/mL.Red: GFR alpha 1 Antibody Blue: DAPI staining](http://images.novusbio.com/fullsize/nbp1-77043_rabbit-polyclonal-gfr-alpha-1-gdnf-r-alpha-1-antibody-2711202419553078.gif)
![Immunohistochemistry: GFR alpha-1/GDNF R alpha-1 Antibody - BSA Free [NBP1-77043] - Immunohistochemistry of GFR alpha 1 in human brain tissue with GFR alpha 1 antibody at 1 ug/mL.](http://images.novusbio.com/fullsize/nbp1-77043_rabbit-polyclonal-gfr-alpha-1-gdnf-r-alpha-1-antibody-271120241923616.jpg)
![Immunohistochemistry: GFR alpha-1/GDNF R alpha-1 Antibody - BSA Free [NBP1-77043] - Immunohistochemistry of GFR alpha 1 in human brain tissue with GFR alpha 1 antibody at 2.5 ug/ml.](http://images.novusbio.com/fullsize/nbp1-77043_rabbit-polyclonal-gfr-alpha-1-gdnf-r-alpha-1-antibody-27112024193773.gif)
![Immunocytochemistry/Immunofluorescence: GFR alpha-1/GDNF R alpha-1 Antibody [NBP2-14045] - Immunofluorescent staining of human cell line U-2 OS shows localization to the Golgi apparatus.](http://images.novusbio.com/fullsize/GFR-alpha-1-GDNF-R-alpha-1-Antibody-Immunocytochemistry-Immunofluorescence-NBP2-14045-img0003.jpg "Immunocytochemistry/Immunofluorescence: GFR alpha-1/GDNF R alpha-1 Antibody [NBP2-14045] - Immunofluorescent staining of human cell line U-2 OS shows localization to the Golgi apparatus.")
![Immunohistochemistry-Paraffin: GFR alpha-1/GDNF R alpha-1 Antibody [NBP2-14045] - Staining of human kidney shows weak granular cytoplasmic positivity in cells in tubules.](http://images.novusbio.com/fullsize/GFR-alpha-1-GDNF-R-alpha-1-Antibody-Immunohistochemistry-Paraffin-NBP2-14045-img0008.jpg)
![Immunohistochemistry-Paraffin: GFR alpha-1/GDNF R alpha-1 Antibody [NBP2-14045] - Staining of human smooth muscle shows strong granular cytoplasmic positivity in smooth muscle cells.](http://images.novusbio.com/fullsize/GFR-alpha-1-GDNF-R-alpha-1-Antibody-Immunohistochemistry-Paraffin-NBP2-14045-img0004.jpg)
![Immunohistochemistry-Paraffin: GFR alpha-1/GDNF R alpha-1 Antibody [NBP2-14045] - Staining of human prostate shows strong granular cytoplasmic positivity in smooth muscle cells.](http://images.novusbio.com/fullsize/GFR-alpha-1-GDNF-R-alpha-1-Antibody-Immunohistochemistry-Paraffin-NBP2-14045-img0005.jpg)
![Immunohistochemistry-Paraffin: GFR alpha-1/GDNF R alpha-1 Antibody [NBP2-14045] - Staining of human colon shows moderate granular cytoplasmic positivity in glandular cells.](http://images.novusbio.com/fullsize/GFR-alpha-1-GDNF-R-alpha-1-Antibody-Immunohistochemistry-Paraffin-NBP2-14045-img0006.jpg)
![Immunohistochemistry-Paraffin: GFR alpha-1/GDNF R alpha-1 Antibody [NBP2-14045] - Staining of human heart muscle shows moderate cytoplasmic positivity in cardiomyocytes.](http://images.novusbio.com/fullsize/GFR-alpha-1-GDNF-R-alpha-1-Antibody-Immunohistochemistry-Paraffin-NBP2-14045-img0007.jpg)
![Western Blot: GDNF Receptor alpha 1 Overexpression Lysate (Adult Normal) [NBP2-10479] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for GDNF Receptor alpha 1.](http://images.novusbio.com/fullsize/GDNF-Receptor-alpha-1-Overexpression-Lysate-Adult-Normal-Western-Blot-NBP2-10479-img0001.jpg "Western Blot: GDNF Receptor alpha 1 Overexpression Lysate (Adult Normal) [NBP2-10479] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for GDNF Receptor alpha 1.")
![Western Blot: GDNF Receptor alpha 1 Overexpression Lysate (Adult Normal) [NBP2-11349] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for GDNF Receptor alpha 1.](http://images.novusbio.com/fullsize/GDNF-Receptor-alpha-1-Overexpression-Lysate-Adult-Normal-Western-Blot-NBP2-11349-img0001.jpg "Western Blot: GDNF Receptor alpha 1 Overexpression Lysate (Adult Normal) [NBP2-11349] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for GDNF Receptor alpha 1.")
![Western Blot: GDNF Receptor alpha 1 Overexpression Lysate (Adult Normal) [NBP2-05472] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for GDNF Receptor alpha 1.](http://images.novusbio.com/fullsize/GDNF-Receptor-alpha-1-Overexpression-Lysate-Adult-Normal-Western-Blot-NBP2-05472-img0001.jpg "Western Blot: GDNF Receptor alpha 1 Overexpression Lysate (Adult Normal) [NBP2-05472] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for GDNF Receptor alpha 1.")