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![Western Blot: Rev-erb beta/NR1D2 Antibody [H00009975-D01P] - Analysis of NR1D2 expression in mouse liver.](http://images.novusbio.com/fullsize/Rev-erb-beta-NR1D2-Antibody-Western-Blot-H00009975-D01P-img0005.jpg "Western Blot: Rev-erb beta/NR1D2 Antibody [H00009975-D01P] - Analysis of NR1D2 expression in mouse liver.")
![Western Blot: Rev-erb beta/NR1D2 Antibody [H00009975-D01P] - Analysis of NR1D2 expression in HeLa.](http://images.novusbio.com/fullsize/Rev-erb-beta-NR1D2-Antibody-Western-Blot-H00009975-D01P-img0004.jpg)
![Western Blot: Rev-erb beta/NR1D2 Antibody [H00009975-D01P] - Analysis of NR1D2 expression in transfected 293T cell line by NR1D2 polyclonal antibody.Lane 1: NR1D2 transfected lysate(64.70 KDa).Lane 2: Non-transfected lysate.](http://images.novusbio.com/fullsize/Rev-erb-beta-NR1D2-Antibody-Western-Blot-H00009975-D01P-img0006.jpg)
![Western Blot: Rev-erb beta/NR1D2 Antibody [NBP2-56141] - Analysis in human cell line RT-4 and human cell line U-251 MG.](http://images.novusbio.com/fullsize/Rev-erb-beta-NR1D2-Antibody-Western-Blot-NBP2-56141-img0002.jpg "Western Blot: Rev-erb beta/NR1D2 Antibody [NBP2-56141] - Analysis in human cell line RT-4 and human cell line U-251 MG.")
![Immunocytochemistry/Immunofluorescence: Rev-erb beta/NR1D2 Antibody [NBP2-56141] - Staining of human cell line PC-3 shows localization to nucleoplasm.](http://images.novusbio.com/fullsize/Rev-erb-beta-NR1D2-Antibody-Immunocytochemistry-Immunofluorescence-NBP2-56141-img0001.jpg)
![Immunohistochemistry: Rev-erb beta/NR1D2 Antibody [NBP2-56141] - Cancer cells from small cell carcinoma employ highly divergent regulatory program compared to adenocarcinoma cells.a,b, Gene set expression scores of single G1 cells using expression signature of NEPC18 (a) & set of genes regulated by AR17 (b). Box plots: center line, median; box limits, upper & lower quartiles; whiskers extend at most 1.5× interquartile range past upper & lower quartiles; P values from 2-sided Mann–Whitney U-test. c, Inferred activity of regulons of different transcriptional regulators. x axis, q values from comparison of inferred regulon activity in cancer cells from small cell carcinoma (n = 76) vs cancer cells from adenocarcinomas (n = 188, sampled as described in Methods) (negative values indicate regulon is less active in small cell carcinoma; two-sided Mann–Whitney U-test, median outcome of sampling iterations (Methods) w/ Bonferroni FWER correction). y axis: P values (two-sided Mann–Whitney U-test, signed as previous) from comparison of expression scores of scRNA-derived regulons in bulk RNA-seq of small cell carcinomas (n = 8) vs adenocarcinomas (n = 18) from a published cohort8. d, Regulon activity in single cells for select transcriptional regulators. e, Hierarchical clustering of bulk RNA-seq of a published cohort of prostate cancers of known histopathology18 based on expression of HOXB5, HOXB6 & NR1D2 regulons inferred from scRNA-seq. B–E correspond to different NEPC subtype labels from original publication. Expression levels of EZH2, NANOG & SOX2 shown for reference but not used in clustering (n = 34 adenocarcinoma, 15 NEPC). f, IHC staining of HOXB5, HOXB6 & NR1D2 protein levels in two prostate adenocarcinoma xenografts (LNCaP & VCaP) & four NEPC patient-derived organoids. Scale bar: 50 μm. Image collected & cropped by CiteAb from following publication (//pubmed.ncbi.nlm.nih.gov/33664492), licensed under a CC-BY license. Not internally tested by Novus Biologicals.](http://images.novusbio.com/fullsize/nbp2-56141_rabbit-polyclonal-rev-erb-beta-nr1d2-antibody-310202416121976.jpg)
![Western Blot: Rev-erb beta/NR1D2 Antibody (1G2) [H00009975-M01] - NR1D2 monoclonal antibody (M01), clone 1G2 Analysis of NR1D2 expression in Hela.](http://images.novusbio.com/fullsize/Rev-erb-beta-NR1D2-Antibody-1G2-Western-Blot-H00009975-M01-img0012.jpg "Western Blot: Rev-erb beta/NR1D2 Antibody (1G2) [H00009975-M01] - NR1D2 monoclonal antibody (M01), clone 1G2 Analysis of NR1D2 expression in Hela.")
![Immunocytochemistry/Immunofluorescence: Rev-erb beta/NR1D2 Antibody (1G2) [H00009975-M01] - Analysis of monoclonal antibody to NR1D2 on HeLa cell. Antibody concentration 10 ug/ml.](http://images.novusbio.com/fullsize/Rev-erb-beta-NR1D2-Antibody-1G2-Immunocytochemistry-Immunofluorescence-H00009975-M01-img0010.jpg)
![Western Blot: Rev-erb beta/NR1D2 Antibody (1G2) [H00009975-M01] - Analysis of NR1D2 over-expressed 293 cell line, cotransfected with NR1D2 Validated Chimera RNAi ( Cat # H00009975-R01V ) (Lane 2) or non-transfected control (Lane 1). Blot probed with NR1D2 monoclonal antibody (M01), clone 1G2 (Cat # H00009975-M01 ). GAPDH ( 36.1 kDa ) used as specificity and loading control.](http://images.novusbio.com/fullsize/Rev-erb-beta-NR1D2-Antibody-1G2-Western-Blot-H00009975-M01-img0011.jpg)
![Western Blot: Rev-erb beta/NR1D2 Antibody (1G2) [H00009975-M01] - Analysis of NR1D2 expression in transfected 293T cell line by NR1D2 monoclonal antibody (M01), clone 1G2.Lane 1: NR1D2 transfected lysate(64.7 KDa).Lane 2: Non-transfected lysate.](http://images.novusbio.com/fullsize/Rev-erb-beta-NR1D2-Antibody-1G2-Western-Blot-H00009975-M01-img0013.jpg)
![Immunohistochemistry-Paraffin: TR alpha/NR1A1/Thyroid Hormone Receptor alpha Antibody [NLS2459] - Anti-NR1D2 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.](http://images.novusbio.com/fullsize/TR-alpha-NR1A1-Thyroid-Hormone-Receptor-alpha-Antibody-Immunohistochemistry-Paraffin-NLS2459-img0006.jpg "Immunohistochemistry-Paraffin: TR alpha/NR1A1/Thyroid Hormone Receptor alpha Antibody [NLS2459] - Anti-NR1D2 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.")
![Immunohistochemistry-Paraffin: TR alpha/NR1A1/Thyroid Hormone Receptor alpha Antibody [NLS2459] - Analysis of anti-NR1D2 antibody with human brain, cerebellum.](http://images.novusbio.com/fullsize/TR-alpha-NR1A1-Thyroid-Hormone-Receptor-alpha-Antibody-Immunohistochemistry-Paraffin-NLS2459-img0005.jpg)
![Immunohistochemistry-Paraffin: Rev-erb beta/NR1D2 Antibody - BSA Free [NBP1-50165] - Analysis of anti-NR1D2 antibody with human heart at 10 ug/ml.](http://images.novusbio.com/fullsize/Rev-erb-beta-NR1D2-Antibody---BSA-Free-Immunohistochemistry-Paraffin-NBP1-50165-img0002.jpg "Immunohistochemistry-Paraffin: Rev-erb beta/NR1D2 Antibody - BSA Free [NBP1-50165] - Analysis of anti-NR1D2 antibody with human heart at 10 ug/ml.")
![Immunohistochemistry-Paraffin: Rev-erb beta/NR1D2 Antibody - BSA Free [NBP1-50165] - Analysis of anti-NR1D2 antibody with human heart at concentration 10 ug/ml.](http://images.novusbio.com/fullsize/Rev-erb-beta-NR1D2-Antibody---BSA-Free-Immunohistochemistry-Paraffin-NBP1-50165-img0001.jpg)
![Western Blot: Rev-erb beta/NR1D2 Antibody [NBP2-47306] - Lane 1: Marker [kDa] 250, 130, 100, 70, 55, 35, 25, 15, 10. Lane 2: Human cell line U-2 OS](http://images.novusbio.com/fullsize/Rev-erb-beta-NR1D2-Antibody-Western-Blot-NBP2-47306-img0002.jpg "Western Blot: Rev-erb beta/NR1D2 Antibody [NBP2-47306] - Lane 1: Marker [kDa] 250, 130, 100, 70, 55, 35, 25, 15, 10. Lane 2: Human cell line U-2 OS")
![Immunohistochemistry: Rev-erb beta/NR1D2 Antibody [NBP2-47306] - Staining of human rectum shows moderate nuclear positivity in glandular cells.](http://images.novusbio.com/fullsize/Rev-erb-beta-NR1D2-Antibody-Immunohistochemistry-NBP2-47306-img0001.jpg)
![Western Blot: Rev-erb beta/NR1D2 Antibody [NBP2-19576] - Sample (30 ug of whole cell lysate) A: NT2D1 7. 5% SDS PAGE gel, diluted at 1:1000.](http://images.novusbio.com/fullsize/NR1D2-Antibody-Western-Blot-NBP2-19576-img0001.jpg "Western Blot: Rev-erb beta/NR1D2 Antibody [NBP2-19576] - Sample (30 ug of whole cell lysate) A: NT2D1 7. 5% SDS PAGE gel, diluted at 1:1000.")
![Immunocytochemistry/Immunofluorescence: Rev-erb beta/NR1D2 Antibody [NBP2-19576] - Sample: HeLa cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: NR1D2 protein stained by NR1D2 antibody, Internal diluted at 1:500. Blue: Hoechst 33343 staining.](http://images.novusbio.com/fullsize/NR1D2-Antibody-Immunocytochemistry-Immunofluorescence-NBP2-19576-img0002.jpg)
![Western Blot: Rev-erb beta/NR1D2 Antibody (5E10) [NBP2-46219] - Analysis of HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY NR1D2.](http://images.novusbio.com/fullsize/Rev-erb-beta-NR1D2-Antibody-5E10-Western-Blot-NBP2-46219-img0001.jpg "Western Blot: Rev-erb beta/NR1D2 Antibody (5E10) [NBP2-46219] - Analysis of HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY NR1D2.")
![Western Blot: NR1D2 Overexpression Lysate (Adult Normal) [NBL1-13766] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for NR1D2.](http://images.novusbio.com/fullsize/NR1D2-Overexpression-Lysate-Adult-Normal-Western-Blot-NBL1-13766-img0002.jpg "Western Blot: NR1D2 Overexpression Lysate (Adult Normal) [NBL1-13766] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for NR1D2.")