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FANCF Products

Antibodies
FANCF Antibody
FANCF Antibody
H00002188-B01P
Species: Hu
Applications: WB, ICC/IF
Host: Mouse Polyclonal
FANCF Antibody
FANCF Antibody
NBP1-51916
Species: Hu
Applications: WB, ELISA
Host: Goat Polyclonal
FANCF Antibody
FANCF Antibody
NBP1-52057
Species: Hu
Applications: WB, ELISA
Host: Goat Polyclonal
Lysates
FANCF Overexpression Lysate
FANCF Overexpression Lysate
NBL1-10588
Species: Hu
Applications: WB
Proteins
FANCF Recombinant Protein Ant ...
FANCF Recombinant Protein Antigen
NBP3-17845PEP
Species: Hu
Applications: AC

Description

FANCF (also called Protein FACF or Fanconi Anemia Group F protein) is involved in DNA repair, perhaps specifically with post-replication repair or a cell cycle checkpoint function. FANCF has also been implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. FANCF belongs to the multi-subunit Fanconi Anemia (FA) complex composed of FANCA, FANCB, FANCC, FANCE, FANCF, FANCG, FANCL/PHF9 and FANCM. The complex is not found in FA patients. FANCF is found within the nucleus. Defects in FANCF are a cause of Fanconi anemia (FA). FA is a genetically heterogeneous, autosomal recessive disorder characterized by progressive pancytopaenia, a diverse assortment of congenital malformations, and a predisposition to the development of malignancies. At the cellular level, it is associated with hypersensitivity to DNA-damaging agents, chromosomal instability (increased chromosome breakage), and defective DNA repair.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Human
Product By Gene ID 2188
Alternate Names
  • FAF
  • Fanconi anemia group F protein
  • Fanconi anemia, complementation group F
  • MGC126856
  • Protein FACF

Related FANCF Blog Posts

Check out the latest blog posts on FANCF.
Fanconi Antibodies and Cancer Research
We at Novus Biologicals have an extensive antibody databasedevoted to the 13 Fanconi anaemia complementation (FANC) genes, which are involved in the recognition and repair of damaged DNA.The core complex of 8 proteins (FANCA, B, C, E, F, G, L and M)...    Read more.
Read more FANCF related blogs.