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Progressive Intrahepatic Cholestasis (disorder): Disease Bioinformatics

Research of Progressive Intrahepatic Cholestasis (disorder) has been linked to Intrahepatic Cholestasis, Cholestasis, Liver Diseases, Liver Cirrhosis, Pruritus. The study of Progressive Intrahepatic Cholestasis (disorder) has been mentioned in research publications which can be found using our bioinformatics tool below. Researched pathways related to Progressive Intrahepatic Cholestasis (disorder) include Transport, Secretion, Excretion, Pathogenesis, Localization. These pathways complement our catalog of research reagents for the study of Progressive Intrahepatic Cholestasis (disorder) including antibodies and ELISA kits against SISTER OF P-GLYCOPROTEIN, JAG1, ALB, ABCC2, F2.

Top Research Reagents

We have 1399 products for the study of Progressive Intrahepatic Cholestasis (disorder) that can be applied to Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Western Blot from our catalog of antibodies and ELISA kits.

ABCB6 Antibody
NBP3-41339
Western Blot: ABCB6 Antibody [NBP3-41339] - Sample: Recombinant protein.Immunohistochemistry-Paraffin: ABCB6 Antibody [NBP3-41339] - Vector Red staining on IHC-P; Samples: Human Testis Tissue; Primary Ab: 10ug/ml NBP3-41339; Second Ab: 2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

GGTLC1 Antibody
NBP1-56928
Western Blot: GGTLC1 Antibody [NBP1-56928] - Antibody Titration: 5.0ug/ml Positive Control: Human kidneyImmunohistochemistry-Paraffin: GGTLC1 Antibody [NBP1-56928] - Human kidney Tissue, antibody concentration 4-8ug/ml. Cells with positive label: renal corpuscle cells (indicated with arrows) 400X magnification.

Rabbit Polyclonal
Species Human
Applications WB, IHC, IHC-P

Prothrombin Antibody
NBP1-58268
721_B tissue lysate at a concentration of 1ug/ml.Immunohistochemistry: Coagulation Factor II/Thrombin Antibody [NBP1-58268] - Analysis of human liver after heat-induced Antigen retrieval. Antibody concentration 5 ug/ml.

Rabbit Polyclonal
Species Human, Mouse
Applications WB, IHC, IHC-P

     1 Review

3 Publications
SLC10A1 Antibody
NBP1-60109
Western Blot: SLC10A1 Antibody [NBP1-60109] - Sample Tissue: Human MDA-MB-435s Antibody Dilution: 1.0 ug/mlWestern Blot: SLC10A1 Antibody [NBP1-60109] - Titration: 0.2-1 ug/ml, Positive Control: HT1080 cell lysate.

Rabbit Polyclonal
Species Human
Applications WB, Flow, B/N

1 Publication
MRP2 Antibody
NBP1-69023
Western Blot: MRP2 Antibody [NBP1-69023] - Sample Tissue: Mouse Thymus Antibody Dilution: 1.0ug/mlWestern Blot: MRP2 Antibody [NBP1-69023] - Mouse Spleen lysate, concentration 0.2-1 ug/ml.

Rabbit Polyclonal
Species Mouse
Applications WB

4 Publications
KLHL1 Antibody - BSA Free
NBP1-76670
Western Blot: KLHL1 Antibody [NBP1-76670] - Analysis of KLHL1 in HeLa cell lysate with KLHL1 antibody at (A) 2 and (B) 4 ug/mL.Immunohistochemistry: KLHL1 Antibody - BSA Free [NBP1-76670] - Immunohistochemistry of KLHL1 in rat brain tissue with KLHL1 antibody at 10 ug/mL.

Rabbit Polyclonal
Species Human, Rat
Applications WB, ELISA, IHC

ABCB11 Antibody
NBP1-89319
Immunohistochemistry-Paraffin: ABCB11 Antibody [NBP1-89319] - Staining in human liver and skeletal muscle tissues . Corresponding ABCB11 RNA-seq data are presented for the same tissues.Immunohistochemistry: ABCB11 Antibody [NBP1-89319] - Histopathology of ABCB11 disease. (a) Giant-cell hepatitis (arrows) with hepatocanalicular cholestasis and (b) complete absence of ABCB11/BSEP protein are typical findings in PFIC2 patients. Inset: immunohistochemical positivity of BSEP in the apical (canalicular) domain of hepatocytes in a healthy control. (a) Hematoxylin and eosin, original magnification x200. (b, inset) Immunohistochemical staining with ABCB11 Rabbit Polyclonal Antibody (NBP1-89319, Novus Biologicals, USA), original magnification x200 (b), x400 (inset). Image collected and cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/30148122) licensed under a CC-BY license.

Rabbit Polyclonal
Species Human
Applications IHC, IHC-P

5 Publications
BRIC Antibody
NBP1-90068
Immunohistochemistry-Paraffin: BRIC Antibody [NBP1-90068] - Staining in human rectum and lymph node tissues using anti-ATP8B1 antibody. Corresponding ATP8B1 RNA-seq data are presented for the same tissues.Immunohistochemistry-Paraffin: BRIC Antibody [NBP1-90068] - Staining of human cerebral cortex, kidney, liver and lymph node using Anti-ATP8B1 antibody NBP1-90068 (A) shows similar protein distribution across tissues to independent antibody NBP1-90067 (B).

Rabbit Polyclonal
Species Human
Applications IHC, IHC-P

MDR3/ABCB4 Antibody
NBP2-30876
Immunohistochemistry-Paraffin: MDR3/ABCB4 Antibody [NBP2-30876] - Staining of human skeletal muscle shows no positivity in myocytes as exected.Immunohistochemistry-Paraffin: MDR3/ABCB4 Antibody [NBP2-30876] - Staining of human cerebral cortex shows no positivity in neurons as expected.

Rabbit Polyclonal
Species Human
Applications IHC, IHC-P

1 Publication
FABP6 Antibody [Unconjugated]
AF3880
FABP6 was detected in immersion fixed T84 human colon carcinoma cell line using Goat Anti-Human FABP6 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF3880) at 10 µg/mL for 3 hours at room temperature. Cells were stained using the NorthernLights™ 557-conjugated Anti-Goat IgG Secondary Antibody (red; Catalog # <a class=

Goat Polyclonal
Species Human
Applications WB, ICC

2 Publications
Albumin Antibody (188835) [Unconjugated] - Serum
MAB1455
Western blot shows lysate of human liver tissue. PVDF membrane was probed with 1 µg/mL of Mouse Anti-Human Serum Albumin Monoclonal Antibody (Catalog # MAB1455) followed by HRP-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # <a class=Albumin was detected in immersion fixed BG01V human embryonic stem cells differentiated to hepatocytes using Mouse Anti-Human Serum Albumin Monoclonal Antibody (Catalog # MAB1455) at 10 µg/mL for 3 hours at room temperature. Cells were stained using the NorthernLights™ 557-conjugated Anti-Mouse IgG Secondary Antibody (red; Catalog # <a class=

Mouse Monoclonal
Species Human
Applications WB, Simple Western, IHC

     3 Reviews

54 Publications
FXR/NR1H4 Antibody (A9033A) [Unconjugated]
PP-A9033A-00

Mouse Monoclonal
Species Human
Applications WB, IHC, IP

     2 Reviews

14 Publications
MRP3 Antibody
NBP2-37923
Immunohistochemistry-Paraffin: MRP3 Antibody [NBP2-37923] - Staining in human stomach and skeletal muscle tissues.. Corresponding ABCC3 RNA-seq data are presented for the same tissues.Immunocytochemistry/Immunofluorescence: MRP3 Antibody [NBP2-37923] - Immunofluorescent staining of human cell line A549 shows localization to plasma membrane. Antibody staining is shown in green.

Rabbit Polyclonal
Species Human
Applications ICC/IF, IHC, IHC-P

Jagged 1 [Unconjugated]
1277-JG


Species Human
Applications BA

45 Publications
Lymphotoxin-alpha/TNF-beta [Unconjugated]
211-TBB/CF
Recombinant Human Lymphotoxin-alpha /TNF-beta (Catalog # 211-TBB/CF) induces cytotoxicity in the L-929 mouse fibroblast cell line in the presence of the metabolic inhibitor actinomycin D. The ED<sub>50</sub> for this effect is 4‑20 pg/mL.1 µg/lane of Recombinant Human Lymphotoxin-alpha /TNF-beta was resolved with SDS-PAGE under reducing (R) conditions and visualized by silver staining, showing a band at 19 kDa.


Species Human
Applications BA

8 Publications
Gamma-glutamyltransferase 2 Antibody
NBP2-46750
Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10, Lane 2: Human cell line RT-4, Lane 3: Human cell line U-251 MG, Lane 4: Human plasma, Lane 5: Human Analysis of human liver tissue. tissue, Lane 6: Human Tonsil tissueStaining of human kidney shows strong cytoplasmic and membranous positivity in tubule cells.

Rabbit Polyclonal
Species Human
Applications WB, IHC, IHC-P

GGT1 Antibody (1F9)
H00002678-M01
Western Blot: GGT1 Antibody (1F9) [H00002678-M01] - GGT1 monoclonal antibody (M01), clone 1F9 Analysis of GGT1 expression in NIH/3T3.Immunohistochemistry-Paraffin: GGT1 Antibody (1F9) [H00002678-M01] - Analysis of monoclonal antibody to GGT1 on formalin-fixed paraffin-embedded human testis. Antibody concentration 3 ug/ml.

Mouse Monoclonal
Species Human, Mouse, Yeast
Applications WB, ELISA, ICC/IF

10 Publications
MDR1/ABCB1 Antibody (SN06-42)
NBP2-67667
Western Blot: MDR1/ABCB1 Antibody (SN06-42) [NBP2-67667] - Analysis of P Glycoprotein on mouse heart tissue lysates. Proteins were transferred to a PVDF membrane and blocked with 5% BSA in PBS for 1 hour at room temperature. The primary antibody (1/500) was used in 5% BSA at room temperature for 2 hours. Goat Anti-Rabbit IgG - HRP Secondary Antibody at 1:200,000 dilution was used for 1 hour at room temperature.Immunohistochemistry-Paraffin: MDR1/ABCB1 Antibody (SN06-42) [NBP2-67667] - Immunohistochemical analysis of paraffin-embedded mouse brain tissue using anti-MDR1/ABCB1 antibody. The section was pre-treated using heat mediated antigen retrieval with Tris-EDTA buffer (pH 8.0-8.4) for 20 minutes. The tissues were blocked in 5% BSA for 30 minutes at room temperature, washed with ddH2O and PBS, and then probed with the primary antibody (1/50) for 30 minutes at room temperature. The detection was performed using an HRP conjugated compact polymer system. DAB was used as the chromogen. Tissues were counterstained with hematoxylin and mounted with DPX.

Rabbit Monoclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

     1 Review

3 Publications
MRP1 Antibody (IU2H10) - BSA Free
NB400-156
Dual RNAscope ISH-IHC: MRP1 Antibody (IU2H10) [NB400-156] - Formalin-fixed paraffin-embedded tissue sections of human testis were probed for MRP1 mRNA (ACD RNAScope Probe, catalog # 435591; Fast Red chromogen, ACD catalog # 322360). Adjacent tissue section was processed for immunohistochemistry using mouse monoclonal (Novus Biologicals catalog # NB400-156) at 7ug/mL with overnight incubation at 4 degrees Celsius followed by incubation with anti-mouse IgG VisUCyte HRP Polymer Antibody (Catalog # VC001) and DAB chromogen (yellow-brown). Tissue was counterstained with hematoxylin (blue). Specific staining was localized to Leydig cells and seminiferous tubule cells.Immunocytochemistry/Immunofluorescence: MRP1 Antibody (IU2H10) [NB400-156] - The MRP-1 antibody was tested in HeLa cells at a 1:50 dilution against Dylight 488 (Green). Alpha tubulin and nuclei were counterstained against Dylight 550 (Red) and DAPI (Blue), respectively.

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, Simple Western, ELISA

17 Publications

Related Genes

Progressive Intrahepatic Cholestasis (disorder) has been researched against:

Related Pathways

Progressive Intrahepatic Cholestasis (disorder) has been linked to:

Related Diseases

Progressive Intrahepatic Cholestasis (disorder) has been studied in relation to diseases such as:

Related PTMs

Progressive Intrahepatic Cholestasis (disorder) has been studied in relation to posttranslational modifications (PTMs) including:

Alternate Names

Progressive Intrahepatic Cholestasis (disorder) is also known as Byler Disease, Byler's Disease, Byler's Syndrome, Familial Intrahepatic Cholestasis, Fatal Intrahepatic Cholestasis.